Mouse Elane ELISA Kit (V2LY-0626-LY183)
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Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae (PubMed:10947984).
Biosynthetic process of antibacterial peptides active against Gram-negative bacteria Source: UniProtKB
Cellular calcium ion homeostasis Source: UniProtKB
Defense response to bacterium Source: UniProtKB
Extracellular matrix disassembly Source: Reactome
Leukocyte migration involved in inflammatory response Source: Ensembl
Negative regulation of chemokine production Source: UniProtKB
Negative regulation of chemotaxis Source: UniProtKB
Negative regulation of inflammatory response Source: UniProtKB
Negative regulation of interleukin-8 production Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Neutrophil-mediated killing of fungus Source: Ensembl
Neutrophil-mediated killing of gram-negative bacterium Source: UniProtKB
Phagocytosis Source: GO_Central
Positive regulation of immune response Source: Ensembl
Positive regulation of interleukin-8 production Source: UniProtKB
Positive regulation of leukocyte tethering or rolling Source: Ensembl
Positive regulation of MAP kinase activity Source: UniProtKB
Positive regulation of smooth muscle cell proliferation Source: UniProtKB
Protein catabolic process Source: UniProtKB
Proteolysis Source: UniProtKB
Pyroptosis Source: Reactome
Response to lipopolysaccharide Source: Ensembl
Response to UV Source: UniProtKB
Response to yeast Source: Ensembl
Autosomal dominant disease in which blood-cell production from the bone marrow oscillates with 21-day periodicity. Circulating neutrophils vary between almost normal numbers and zero. During intervals of neutropenia, affected individuals are at risk for opportunistic infection. Monocytes, platelets, lymphocytes and reticulocytes also cycle with the same frequency.
Neutropenia, severe congenital 1, autosomal dominant (SCN1):
A disorder of hematopoiesis characterized by maturation arrest of granulopoiesis at the level of promyelocytes with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/l and early onset of severe bacterial infections.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human ELANE ELISA Kit (CAT#: V2LY-0626-LY1234)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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