Mouse Il19 ELISA Kit (V2LY-0626-LY5840)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.0032 ng/mL
Detection Range
0.007-1.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
20.3 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Interleukin 19
Function
May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis (By similarity).
Biological Process
Apoptotic process Source: UniProtKB-KW
Immune response Source: UniProtKB
Negative regulation of extrinsic apoptotic signaling pathway Source: Ensembl
Negative regulation of low-density lipoprotein particle clearance Source: Ensembl
Positive regulation of intrinsic apoptotic signaling pathway Source: Ensembl
Reactive oxygen species metabolic process Source: Ensembl
Signal transduction Source: UniProtKB
Cellular Location
Secreted

Della Bella, C., Antico, A., Panozzo, M. P., Capitani, N., Benagiano, M., Petrone, L., ... & D’Elios, M. M. (2022). Elevated IL-19 serum levels in patients with pernicious anemia and autoimmune gastritis. Frontiers in Immunology, 13, 887256.

Chen, W., Xing, J., Liu, X., Wang, S., & Xing, D. (2021). The role and transformative potential of IL-19 in atherosclerosis. Cytokine & Growth Factor Reviews, 62, 70-82.

Azuma, Y. T., Fujita, T., Izawa, T., Hirota, K., Nishiyama, K., Ikegami, A., ... & Tsuneyama, K. (2021). Il-19 contributes to the development of nonalcoholic steatohepatitis by altering lipid metabolism. Cells, 10(12), 3513.

Dogan, M., Sahin, M., & Yenisey, C. (2019). Increased TSLP, IL-33, IL-25, IL-19, IL 21 and amphiregulin (AREG) levels in chronic rhinosinusitis with nasal polyp. European Archives of Oto-Rhino-Laryngology, 276, 1685-1691.

An, W., Yu, Y., Zhang, Y., Zhang, Z., Yu, Y., & Zhao, X. (2019). Exogenous IL‐19 attenuates acute ischaemic injury and improves survival in male mice with myocardial infarction. British journal of pharmacology, 176(5), 699-710.

Weng, Y. H., Chen, W. Y., Lin, Y. L., Wang, J. Y., & Chang, M. S. (2019). Blocking IL-19 signaling ameliorates allergen-induced airway inflammation. Frontiers in Immunology, 10, 968.

Konrad, R. J., Higgs, R. E., Rodgers, G. H., Ming, W., Qian, Y. W., Bivi, N., ... & Nickoloff, B. J. (2019). Assessment and clinical relevance of serum IL-19 levels in psoriasis and atopic dermatitis using a sensitive and specific novel immunoassay. Scientific Reports, 9(1), 5211.

Ray, M., Gabunia, K., Vrakas, C. N., Herman, A. B., Kako, F., Kelemen, S. E., ... & Autieri, M. V. (2018). Genetic deletion of IL-19 (interleukin-19) exacerbates atherogenesis in Il19−/−× Ldlr−/− double knockout mice by dysregulation of mRNA stability protein HuR (human antigen R). Arteriosclerosis, thrombosis, and vascular biology, 38(6), 1297-1308.

Autieri, M. V. (2018). IL-19 and other IL-20 family member cytokines in vascular inflammatory diseases. Frontiers in Immunology, 9, 700.

Herman, A. B., Vrakas, C. N., Ray, M., Kelemen, S. E., Sweredoski, M. J., Moradian, A., ... & Autieri, M. V. (2018). FXR1 is an IL-19-responsive RNA-binding protein that destabilizes pro-inflammatory transcripts in vascular smooth muscle cells. Cell reports, 24(5), 1176-1189.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human IL19 ELISA Kit (CAT#: V2LY-0626-LY4005)

Human Recombinant IL19 protein, His Tag (CAT#: V2LY-0526-LY4801)

Human Recombinant IL19 protein, His Tag-1 (CAT#: V2LY-0526-LY4802)

Human Recombinant IL19 protein, His Tag-2 (CAT#: V2LY-0526-LY4803)

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Mouse Anti-IL19 Recombinant Antibody (CBYY-I1345) (CAT#: CBMAB-I2515-YY)

Mouse Anti-IL19 Recombinant Antibody (A491) (CAT#: CBMAB-AP10833LY)

Mouse Anti-IL19 (AA 0411-10) Recombinant Antibody (MM0383-1G54) (CAT#: CBMAB-I0884-YY)

Mouse Anti-IL19 Recombinant Antibody (152112) (CAT#: CBMAB-I0434-YY)

Mouse Anti-IL19 Recombinant Antibody (CBYY-I0153) (CAT#: CBMAB-I0433-YY)

Human Recombinant IL19 protein, His Tag-2 (CAT#: V2LY-0526-LY4803)

Mouse Anti-IL19 Recombinant Antibody (CF226) (CAT#: CBMAB-FT250LY)

Human Recombinant IL19 protein, His Tag-1 (CAT#: V2LY-0526-LY4802)

Isotype control

For research use only. Not intended for any clinical use.

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