Mouse Ltbr ELISA Kit (V2LY-0626-LY3169)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.01 ng/mL
Detection Range
0.02-3.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
45.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
LTBR
Function
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Biological Process
Apoptotic processIEA:UniProtKB-KW
Cellular response to mechanical stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Immune responseIEA:InterPro
Myeloid dendritic cell differentiationIEA:Ensembl
Positive regulation of extrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of I-kappaB kinase/NF-kappaB signalingManual Assertion Based On ExperimentIEP:UniProtKB
Positive regulation of JNK cascadeManual Assertion Based On ExperimentIMP:UniProtKB
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 31-227
Helical: 228-248
Cytoplasmic: 249-435

Miki, H., Kiosses, W. B., Manresa, M. C., Gupta, R. K., Sethi, G. S., Herro, R., ... & Croft, M. (2023). Lymphotoxin beta receptor signaling directly controls airway smooth muscle deregulation and asthmatic lung dysfunction. Journal of Allergy and Clinical Immunology, 151(4), 976-990.

Saxena, V., Piao, W., Li, L., Paluskievicz, C., Xiong, Y., Simon, T., ... & Bromberg, J. S. (2022). Treg tissue stability depends on lymphotoxin beta-receptor-and adenosine-receptor-driven lymphatic endothelial cell responses. Cell reports, 39(3).

Legut, M., Guarino, M., Xue, X., Lu, C., Vyas, R., Diefenbach, C. S., & Sanjana, N. (2022). Preclinical Development of Lymphotoxin Beta Receptor-Overexpressing CAR T Cells Demonstrates Potentiation of CAR T Cell Antitumor Activity. Blood, 140(Supplement 1), 10235-10236.

Chen, Y. G. (2022). Investigating the role of the linear ubiquitin chain assembly complex in lymphotoxin beta receptor signalling and obesity-derived hepatitis (Doctoral dissertation, UCL (University College London)).

Shou, Y., Koroleva, E., Spencer, C. M., Shein, S. A., Korchagina, A. A., Yusoof, K. A., ... & Tumanov, A. V. (2021). Redefining the role of lymphotoxin beta receptor in the maintenance of lymphoid organs and immune cell homeostasis in adulthood. Frontiers in immunology, 12, 712632.

Francipane, M. G., Han, B., & Lagasse, E. (2020). Host lymphotoxin-β receptor signaling is crucial for angiogenesis of metanephric tissue transplanted into lymphoid sites. The American Journal of Pathology, 190(1), 252-269.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant LTBR protein, hFc Tag (CAT#: V2LY-0526-LY1601)

Human Recombinant LTBR protein, hFc Tag (CAT#: V2LY-0526-LY5405)

Rat Recombinant LTBR protein, hFc Tag (CAT#: V2LY-0526-LY9515)

Rat Recombinant LTBR protein, His Tag (CAT#: V2LY-0526-LY9516)

Human LTBR ELISA Kit (CAT#: V2LY-0626-LY5387)

LTBR Matched Antibody Pair (700) (CAT#: APMAB-700LY)

LTBR Matched Antibody Pair (701) (CAT#: APMAB-701LY)

Antibody Pairs

LTBR Matched Antibody Pair (700) (CAT#: APMAB-700LY)

LTBR Matched Antibody Pair (701) (CAT#: APMAB-701LY)

Related Products

Cynomolgus Recombinant LTBR protein, hFc Tag (CAT#: V2LY-0526-LY1601)

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2153) (CAT#: CBMAB-L2332-YJ)

Rat Anti-Ltbr Recombinant Antibody (3C8) (CAT#: CBMAB-L2944-YJ)

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2150) (CAT#: CBMAB-L2327-YJ)

Mouse Anti-LTBR Recombinant Antibody (7E3) (CAT#: CBMAB-A5120-LY)

Rat Anti-Ltbr Recombinant Antibody (CBYJL-2538) (CAT#: CBMAB-L2952-YJ)

Rat Anti-Ltbr Recombinant Antibody (CBYJT-3851) (CAT#: CBMAB-T3246-YJ)

Rat Anti-Ltbr Recombinant Antibody (CBYJL-2530) (CAT#: CBMAB-L2939-YJ)

Rat Anti-Ltbr Recombinant Antibody (CBYJT-1435) (CAT#: CBMAB-T0459-YJ)

Mouse Anti-LTBR Recombinant Antibody (MM0461-3T24) (CAT#: CBMAB-L2352-YJ)

Isotype control

For research use only. Not intended for any clinical use.

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