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LTBR

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis. [provided by RefSeq]
Full Name
LTBR
Function
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Biological Process
Apoptotic processIEA:UniProtKB-KW
Cellular response to mechanical stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Immune responseIEA:InterPro
Myeloid dendritic cell differentiationIEA:Ensembl
Positive regulation of extrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of I-kappaB kinase/NF-kappaB signalingManual Assertion Based On ExperimentIEP:UniProtKB
Positive regulation of JNK cascadeManual Assertion Based On ExperimentIMP:UniProtKB
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 31-227
Helical: 228-248
Cytoplasmic: 249-435

Anti-LTBR antibodies

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Mouse Anti-LTBR Recombinant Antibody (7H156) (CBMAB-L2345-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 7H156
Application*: E, F

Rat Anti-LTBR Recombinant Antibody (CBYJL-2601) (CBMAB-L2348-YJ)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2601
Application*: F, IP

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2166) (CBMAB-L2350-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYJL-2166
Application*: WB, IP, IF, E

Rat Anti-Ltbr Recombinant Antibody (5G11) (CBMAB-L2946-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: 5G11
Application*: FC

Mouse Anti-LTBR Recombinant Antibody (CBYCL-535) (CBMAB-L0436-YC)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-535
Application*: E, F

Rat Anti-LTBR Recombinant Antibody (CBYCL-536) (CBMAB-L0437-YC)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-536
Application*: F, IP

Rat Anti-LTBR Recombinant Antibody (CBYCL-537) (CBMAB-L0438-YC)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYCL-537
Application*: F, FN

Rat Anti-LTBR Recombinant Antibody (CBYCL-538) (CBMAB-L0439-YC)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYCL-538
Application*: F

Rat Anti-LTBR Recombinant Antibody (CBYCL-539) (CBMAB-L0440-YC)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-539
Application*: F, IP

Rat Anti-Ltbr Recombinant Antibody (CBYJL-2530) (CBMAB-L2939-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJL-2530
Application*: FC

Rat Anti-Ltbr Recombinant Antibody (157108) (CBMAB-L2943-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 157108
Application*: FC

Mouse Anti-LTBR Recombinant Antibody (5E2) (CBMAB-A5119-LY)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5E2
Application*: E, E

Mouse Anti-LTBR Recombinant Antibody (7E3) (CBMAB-A5120-LY)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 7E3
Application*: E, E

Recombinant Rat Anti-LTBR Antibody (CBHb059) (CBMAB-Hb680-LY)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBHb059
Application*: FC, FuncS, Immuno assays, WB

Mouse Anti-LTBR Recombinant Antibody (CBYJT-1434) (CBMAB-T0458-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYJT-1434
Application*: WB, IC, P, C, E

Mouse Anti-LTBR Recombinant Antibody (CBYJT-1433) (CBMAB-T0457-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1433
Application*: F

Rat Anti-Ltbr Recombinant Antibody (CBYJT-1435) (CBMAB-T0459-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYJT-1435
Application*: F, WB

Rat Anti-LTBR Recombinant Antibody (CBFYA-0039) (CBMAB-X0058-FY)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYA-0039
Application*: F, FN, IA, WB

Rat Anti-Ltbr Recombinant Antibody (CBYJT-3851) (CBMAB-T3246-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJT-3851
Application*: WB

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2167) (CBMAB-L2351-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-2167
Application*: F

Mouse Anti-LTBR Recombinant Antibody (MM0461-3T24) (CBMAB-L2352-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0461-3T24
Application*: WB, F

Rat Anti-Ltbr Recombinant Antibody (YTS213.1) (CBMAB-L2953-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: YTS213.1
Application*: FC

Rat Anti-Ltbr Recombinant Antibody (CBYJL-2538) (CBMAB-L2952-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJL-2538
Application*: WB, FC

Recombinant Anti-Ltbr Recombinant Antibody (CBYJL-2537) (CBMAB-L2951-YJ)

Datasheet SDS
Target: Ltbr
Host: Recombinant
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYJL-2537
Application*: FC

Rat Anti-Ltbr Recombinant Antibody (3C8) (CBMAB-L2944-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: 3C8
Application*: FC

Rat Anti-Ltbr Recombinant Antibody (CBYJL-2532) (CBMAB-L2941-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJL-2532
Application*: WB

Rat Anti-Ltbr Recombinant Antibody (CBYJL-2531) (CBMAB-L2940-YJ)

Datasheet SDS
Target: Ltbr
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJL-2531
Application*: FC, WB

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2150) (CBMAB-L2327-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2150
Application*: F, WB

Rat Anti-LTBR Recombinant Antibody (CBYJL-2151) (CBMAB-L2328-YJ)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-2151
Application*: F, IP

Mouse Anti-LTBR Recombinant Antibody (31G4D8) (CBMAB-L2329-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 31G4D8
Application*: E, F, IP, WB

Mouse Anti-LTBR Recombinant Antibody (3G10) (CBMAB-L2330-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G10
Application*: WB

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2152) (CBMAB-L2331-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2152
Application*: F, WB

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2153) (CBMAB-L2332-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2153
Application*: E

Rat Anti-LTBR Recombinant Antibody (6D66) (CBMAB-L2338-YJ)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: 6D66
Application*: F, IP

Rat Anti-LTBR Recombinant Antibody (CBYJL-2160) (CBMAB-L2340-YJ)

Datasheet SDS
Target: LTBR
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2160
Application*: E, F, FN

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2161) (CBMAB-L2341-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2161
Application*: AG

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2162) (CBMAB-L2342-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-2162
Application*: F

Mouse Anti-LTBR Recombinant Antibody (CBYJL-2163) (CBMAB-L2343-YJ)

Datasheet SDS
Target: LTBR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2163
Application*: E

LTBR Matched Antibody Pair (701) (APMAB-701LY)

Datasheet SDS
Target: LTBR
Specificity: Human

LTBR Matched Antibody Pair (700) (APMAB-700LY)

Datasheet SDS
Target: LTBR
Specificity: Human
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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