Mouse Recombinant ASAM protein, His Tag (V2LY-0526-LY7827)

Name: Mouse Recombinant ASAM protein, His Tag
SKU: V2LY-0526-LY7827
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

His Tag

Protein Construction

This product is Mouse Recombinant ASAM protein, His Tag consist of Amino Acid: 1-232 and predicts a molecular mass of 25.6 kDa.

Molecule Mass

25.6 kDa

Sequence

Amino Acid: 1-232

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥95% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

CXADR Like Membrane Protein

Function

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.

Biological Process

Digestive tract development Source: UniProtKB

Cellular Location

Cell membrane; Tight junction

Involvement in disease

Congenital short bowel syndrome (CSBS):
A disease characterized by a shortened small intestine, intestinal malrotation, and malabsorption. The mean length of the small intestine in CSBS patients is approximately 50 cm, compared with a normal length at birth of 190-280 cm. Patients with CSBS may develop severe malnutrition as a result of the hugely reduced absorptive surface of the small intestine. Infants require parenteral nutrition for survival. However, parenteral nutrition itself causes life-threatening complications such as sepsis and liver failure which are associated with a high rate of mortality early in life.

Topology

Extracellular: 19-235
Helical: 236-256
Cytoplasmic: 257-373

Mamoor, S. (2021). Differential expression of CXADR-like membrane protein in cancers of the breast.

Han, X., Zhao, Z. A., Yan, S., Lei, W., Wu, H., Lu, X. A., ... & Hu, S. (2020). CXADR‐like membrane protein protects against heart injury by preventing excessive pyroptosis after myocardial infarction. Journal of cellular and molecular medicine, 24(23), 13775-13788.

Chuang, Y. H., Fan, W. L., Chu, Y. D., Liang, K. H., Yeh, Y. M., Chen, C. C., ... & Lai, M. W. (2020). Whole-Exome Sequencing Identified Novel CLMP Mutations in a Family With Congenital Short Bowel Syndrome Presenting Differently in Two Probands. Frontiers in Genetics, 11, 1610.

Gharesouran, J., Esfahani, B. S., Valilou, S. F., Moradi, M., Mousavi, M. H., & Rezazadeh, M. (2019). First report of congenital short bowel syndrome in an Iranian patient caused by a mutation in the CLMP gene. Journal of pediatric genetics, 8(02), 073-080.

Langhorst, H., Jüttner, R., Groneberg, D., Mohtashamdolatshahi, A., Pelz, L., Purfürst, B., ... & Rathjen, F. G. (2018). The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice. Disease models & mechanisms, 11(2), dmm032128.

Nusrat, A., Parkos, C. A., & Luissint, A. C. (2018). CLMP-mediated regulation of intestinal homeostasis in IBD. University of Michigan Ann Arbor United States.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant ASAM protein, His Tag (CAT#: V2LY-0526-LY2179)

Rat Recombinant ASAM protein, His Tag (CAT#: V2LY-0526-LY9165)

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Human Recombinant ASAM protein, His Tag (CAT#: V2LY-0526-LY2179)

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Rabbit Anti-CLMP Recombinant Antibody (C4235) (CAT#: CBMAB-C4235-LY)

Rat Recombinant ASAM protein, His Tag (CAT#: V2LY-0526-LY9165)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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