Mouse Recombinant TMED1 protein, hFc Tag (V2LY-0526-LY8993)

Name: Mouse Recombinant TMED1 protein, hFc Tag
SKU: V2LY-0526-LY8993
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

hFc Tag

Protein Construction

This product is Mouse Recombinant TMED1 protein, hFc Tag consist of Amino Acid: 1-194 and predicts a molecular mass of 46 kDa.

Molecule Mass

46 kDa

Sequence

Amino Acid: 1-194

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>85% as determined by SDS-PAGE.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Transmembrane P24 Trafficking Protein 1

Function

Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1 (PubMed:23319592).
Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26 (PubMed:32614325).

Biological Process

Biological Process cell-cell signalingSource:ProtInc1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transportSource:GO_Central1 Publication
Biological Process Golgi organizationSource:GO_Central1 Publication
Biological Process innate immune responseSource:UniProtKB-KW
Biological Process intracellular protein transportSource:GO_Central1 Publication
Biological Process signal transductionSource:ProtInc1 Publication

Cellular Location

Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus, cis-Golgi network membrane
Endoplasmic reticulum-Golgi intermediate compartment membrane

Topology

Extracellular: 24-194
Helical: 195-215
Cytoplasmic: 216-227

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant TMED1 protein, hFc Tag (CAT#: V2LY-0526-LY7278)

Human Recombinant TMED1 protein, His Tag (CAT#: V2LY-0526-LY7279)

Related Products

Mouse Anti-TMED1 Recombinant Antibody (CBYJT-3460) (CAT#: CBMAB-T2784-YJ)

Mouse Anti-TMED1 Recombinant Antibody (CBYJT-3459) (CAT#: CBMAB-T2783-YJ)

Human Recombinant TMED1 protein, His Tag (CAT#: V2LY-0526-LY7279)

Human Recombinant TMED1 protein, hFc Tag (CAT#: V2LY-0526-LY7278)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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