Mouse Recombinant VSIR protein, ECD, His Tag (V2LY-0526-LY9069)

Name: Mouse Recombinant VSIR protein, ECD, His Tag
SKU: V2LY-0526-LY9069
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

His Tag

Protein Construction

This product is Mouse Recombinant VSIR protein, ECD, His Tag consist of Amino Acid: 1-191 and predicts a molecular mass of 19.2 kDa.

Molecule Mass

19.2 kDa

Protein Domain

ECD

Verified

HPLC

Sequence

Amino Acid: 1-191

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥95% as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile ACN, TFA

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

V-set immunoregulatory receptor

Function

Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993).
May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity).
May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).

Biological Process

Biological Process negative regulation of alpha-beta T cell activation Source:GO_Central1 Publication
Biological Process negative regulation of CD4-positive, alpha-beta T cell proliferation Source:UniProtKB1 Publication
Biological Process negative regulation of CD8-positive, alpha-beta T cell proliferation Source:UniProtKB1 Publication
Biological Process negative regulation of interleukin-10 production Source:UniProtKB1 Publication
Biological Process negative regulation of interleukin-17 production Source:UniProtKB1 Publication
Biological Process negative regulation of tumor necrosis factor production Source:UniProtKB1 Publication
Biological Process negative regulation of type II interferon production Source:UniProtKB1 Publication
Biological Process positive regulation of cell migration Source:UniProtKB1 Publication
Biological Process positive regulation of collagen catabolic process Source:UniProtKB1 Publication
Biological Process positive regulation of endopeptidase activity Source:UniProtKB1 Publication
Biological Process positive regulation of gene expression Source:UniProtKB1 Publication
Biological Process positive regulation of regulatory T cell differentiation Source:UniProtKB1 Publication
Biological Process regulation of immune response Source:InterPro
Biological Process zymogen activation Source:UniProtKB1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 33-194
Helical: 195-215
Cytoplasmic: 216-311

PTM

At the cell surface, may be cleaved by MMP14.
N-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant VISTA protein, hFc Tag (CAT#: V2LY-0526-LY1669)

Cynomolgus Recombinant VISTA protein, His Tag (CAT#: V2LY-0526-LY1670)

Human Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY7628)

Human Recombinant VSIR protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY7629)

Human Recombinant VSIR protein, His Tag (CAT#: V2LY-0526-LY7630)

Mouse Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY9067)

Mouse Recombinant VSIR protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY9068)

Rat Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY9638)

Rhesus Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY9802)

Rhesus Recombinant VSIR protein, ECD, His Tag (CAT#: V2LY-0526-LY9803)

Related Products

Rhesus Recombinant VSIR protein, ECD, His Tag (CAT#: V2LY-0526-LY9803)

Cynomolgus Recombinant VISTA protein, hFc Tag (CAT#: V2LY-0526-LY1669)

Rat Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY9638)

Mouse Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY9067)

Mouse Anti-VSIR Recombinant Antibody (MM0741-29N17) (CAT#: CBMAB-G6682-LY)

Mouse Anti-VSIR Recombinant Antibody (730804) (CAT#: CBMAB-G1226-LY)

Mouse Anti-VSIR Recombinant Antibody (CBWJC-4580) (CAT#: CBMAB-C5984WJ)

Rhesus Recombinant VSIR protein, ECD, hFc Tag (CAT#: V2LY-0526-LY9802)

Mouse Anti-VSIR Recombinant Antibody (CBT4087) (CAT#: V2LY-0625-LY830)

Mouse Recombinant VSIR protein, ECD, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY9068)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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