Mouse Sesn3 ELISA Kit (V2LY-0626-LY1750)

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Tested Data
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Basic Information

Sensitivity
0.024 ng/mL
Detection Range
0.05-30 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
57.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
sestrin 3
Function
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562).
May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity).
This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).
May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein (By similarity).
Biological Process
Biological Process cellular response to amino acid starvationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cellular response to glucose starvationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cellular response to leucineManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to leucine starvationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process glucose homeostasisIEA:Ensembl
Biological Process negative regulation of TORC1 signalingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of macroautophagyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of insulin receptor signaling pathwayIEA:Ensembl
Biological Process regulation of protein kinase B signalingIEA:Ensembl
Biological Process regulation of response to reactive oxygen speciesIEA:InterPro
Biological Process response to insulinIEA:Ensembl
Biological Process TORC2 signalingIEA:Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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