Mouse Slc32a1 ELISA Kit (V2LY-0626-LY3205)

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Tested Data
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Basic Information

Sensitivity
0.0016 ng/mL
Detection Range
0.003-0.9 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
57.4 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Solute Carrier Family 32 Member 1
Function
Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient (By similarity).
May also transport beta-alanine (By similarity).
Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (By similarity).
Biological Process
Biological Process agingIEA:Ensembl
Biological Process amino acid transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process beta-alanine transportISS:UniProtKB
Biological Process gamma-aminobutyric acid importISS:UniProtKB
Biological Process gamma-aminobutyric acid transportISS:UniProtKB
Biological Process glycine transportISS:UniProtKB
Biological Process hippocampus developmentIEA:Ensembl
Biological Process ion transportTAS:Reactome
Biological Process neurotransmitter loading into synaptic vesicleManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neurotransmitter secretionTAS:Reactome
Cellular Location
Cytoplasmic vesicle membrane
Presynapse
Presents in glycine-, GABA- or GABA- and glycine-containing boutons.
Topology
Cytoplasmic: 1-132
Helical: 133-153
Lumenal: 154-204
Helical: 205-225
Cytoplasmic: 226-265
Helical: 266-286
Lumenal: 287-305
Helical: 306-326
Cytoplasmic: 327-341
Helical: 342-362
Lumenal: 363-383
Helical: 384-404
Cytoplasmic: 405-438
Helical: 439-459
Lumenal: 460-461
Helical: 462-482
Cytoplasmic: 483-489
Helical: 490-510
Lumenal: 490-510
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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