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NHLH2 Matched Antibody Pair (799) (APMAB-799LY)

This antibody pair set can be used for detecting and quantifying protein level of human NHLH2.
See all NHLH2 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-NHLH2 monoclonal, IgG2a antibody, 100 ug
Detection Antibody
Anti-NHLH2 Biotinylated mouse monoclonal, IgG2a antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Alternative Names
Nescient Helix-Loop-Helix 2; Class A Basic Helix-Loop-Helix Protein 34; Nescient Helix Loop Helix 2; BHLHa34; NSCL-2; HEN-2;
Entrez Gene ID
UniProt ID

Madsen, A. T., & Good, D. J. (2023). In Silico Examination of Single Nucleotide Missense Mutations in NHLH2, a Gene Linked to Infertility and Obesity. International Journal of Molecular Sciences, 24(4), 3193.

Topaloglu, A. K., Simsek, E., Kocher, M. A., Mammadova, J., Bober, E., Kotan, L. D., ... & Good, D. J. (2022). Inactivating NHLH2 variants cause idiopathic hypogonadotropic hypogonadism and obesity in humans. Human Genetics, 141(2), 295-304.

Kummerfeld, D. M., Skryabin, B. V., Brosius, J., Vakhrushev, S. Y., & Rozhdestvensky, T. S. (2022). Reference genes across nine brain areas of wild type and Prader-Willi Syndrome mice: Assessing differences in Igfbp7, Pcsk1, Nhlh2 and Nlgn3 expression. International Journal of Molecular Sciences, 23(15), 8729.

Katzendorn, O., Peters, I., Dubrowinskaja, N., Moog, J. M., Reese, C., Tezval, H., ... & Serth, J. (2021). DNA methylation in INA, NHLH2, and THBS4 is associated with metastatic disease in renal cell carcinoma. Cancers, 14(1), 39.

Carraro, R. S., Nogueira, G. A., Sidarta-Oliveira, D., Gaspar, R. S., Dragano, N. R., Morari, J., ... & Velloso, L. A. (2021). Arcuate nucleus overexpression of NHLH2 reduces body mass and attenuates obesity-associated anxiety/depression-like behavior. Journal of Neuroscience, 41(48), 10004-10022.

Leon, S., Talbi, R., McCarthy, E. A., Ferrari, K., Fergani, C., Naule, L., ... & Navarro, V. M. (2021). Sex-specific pubertal and metabolic regulation of Kiss1 neurons via Nhlh2. Elife, 10, e69765.

Kocher, M. A., Huang, F. W., Le, E., & Good, D. J. (2021). Snord116 post-transcriptionally increases Nhlh2 mRNA stability: implications for human Prader-Willi syndrome. Human Molecular Genetics, 30(12), 1101-1110.

Hadziselimovic, F., Verkauskas, G., & Stadler, M. B. (2021). Molecular clues in the regulation of mini‐puberty involve neuronal DNA binding transcription factor NHLH2. Basic and clinical andrology, 31, 1-13.

Afshar, H., Adelirad, F., Kowsari, A., Kalhor, N., Delbari, A., Najafipour, R., ... & Ohadi, M. (2020). Natural selection at the NHLH2 core promoter exceptionally long CA-repeat in human and disease-only genotypes in late-onset neurocognitive disorder. Gerontology, 66(5), 514-522.

Li, W., Guo, B., Tao, K., Li, F., Liu, Z., Yao, H., ... & Liu, X. (2019). Inhibition of SIRT1 in hippocampal CA1 ameliorates PTSD-like behaviors in mice by protections of neuronal plasticity and serotonin homeostasis via NHLH2/MAO-A pathway. Biochemical and Biophysical Research Communications, 518(2), 344-350.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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