PANK4 Matched Antibody Pair (840) (APMAB-840LY)

Name: PANK4 Matched Antibody Pair (840)
SKU: APMAB-840LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-PANK4 monoclonal, IgG2a antibody, 100 ug

Detection Antibody

Anti-PANK4 Biotinylated mouse monoclonal, IgG2a antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008]

Alternative Names

Pantothenate Kinase 4; Pantothenic Acid Kinase 4; EC 2.7.1.33; HPanK4;

Entrez Gene ID

55229

UniProt ID

Q9NVE7

More Infomation

References

Vella, V., Ditsiou, A., Chalari, A., Eravci, M., Wooller, S. K., Gagliano, T., ... & Giamas, G. (2024). Kinome‐Wide Synthetic Lethal Screen Identifies PANK4 as a Modulator of Temozolomide Resistance in Glioblastoma. Advanced Science, 2306027.

Vella, V., Ditsiou, A., Chalari, A., Eravci, M., Wooler, S. K., Gagliano, T., ... & Zhang, Y. (2023). Kinome-wide synthetic lethal screen identifies PANK4 as modulator of resistance in glioblastoma.

Guan, J., Zhang, L., & Zhou, F. (2022). PI3K-PANK4: a new target for de novo synthesis of coenzyme A. Molecular Biomedicine, 3(1), 33.

Sun, M., Chen, C., Hou, S., Li, X., Wang, H., Zhou, J., ... & Ye, J. (2019). A novel mutation of PANK4 causes autosomal dominant congenital posterior cataract. Human mutation, 40(4), 380-391.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-PANK4 Recombinant Antibody (CBYC-P157)

Rabbit Anti-PANK4 Recombinant Antibody (D8N2C)

Mouse Anti-PANK4 Recombinant Antibody (3C1)

Rabbit Anti-PANK4 Recombinant Antibody (D6J4R)

Mouse Anti-PANK4 Recombinant Antibody (4F10)

Mouse Anti-PANK4 Recombinant Antibody (2A11)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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