Rabbit CACNA2D1 ELISA Kit (V2LY-0626-LY548)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.09 ng/mL
Detection Range
0.2-60 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rabbit
Assay Type
Sandwich
Reactivity
Rabbit
Assay Time
1.5 h
Molecule Mass
125.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
CALCIUM VOLTAGE-GATED CHANNEL AUXILIARY SUBUNIT ALPHA2DELTA 1
Function
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).
Biological Process
Calcium ion import across plasma membrane Source: BHF-UCL
Calcium ion transmembrane transport via high voltage-gated calcium channel Source: BHF-UCL
Calcium ion transport Source: UniProtKB
Calcium ion transport into cytosol Source: BHF-UCL
Cardiac muscle cell action potential involved in contraction Source: BHF-UCL
Cellular response to amyloid-beta Source: ARUK-UCL
Membrane depolarization during bundle of His cell action potential Source: BHF-UCL
Positive regulation of high voltage-gated calcium channel activity Source: BHF-UCL
Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel Source: ARUK-UCL
Regulation of calcium ion transport Source: BHF-UCL
Regulation of heart rate by cardiac conduction Source: BHF-UCL
Regulation of membrane repolarization during action potential Source: BHF-UCL
Regulation of ventricular cardiac muscle cell membrane repolarization Source: BHF-UCL
Cellular Location
Membrane
Topology
Extracellular: 25-1073 aa
Helical: 1074-1094 aa
Cytoplasmic: 1095-1103 aa
PTM
Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked.

Ye, Y., Barghouth, M., Luan, C., Kazim, A., Zhou, Y., Eliasson, L., ... & Renström, E. (2020). The TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells. Molecular and cellular endocrinology, 502, 110673.

Sun, L., Wang, G., He, M., Mei, Z., Zhang, F., & Liu, P. (2020). Effect and mechanism of the CACNA2D1-CGRP pathway in osteoarthritis-induced ongoing pain. Biomedicine & Pharmacotherapy, 129, 110374.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Cacna2d1 ELISA Kit (CAT#: V2LY-0626-LY2829)

Human CACNA2D1 ELISA Kit (CAT#: V2LY-0626-LY4186)

Related Products

Mouse Anti-CACNA2D1 Recombinant Antibody (20A) (CAT#: CBMAB-1264-CN)

Rat Cacna2d1 ELISA Kit (CAT#: V2LY-0626-LY2829)

Human CACNA2D1 ELISA Kit (CAT#: V2LY-0626-LY4186)

Mouse Anti-CACNA2D1 Recombinant Antibody (CBFYC-0720) (CAT#: CBMAB-C0775-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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