Rat Cd48 ELISA Kit (V2LY-0626-LY2118)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.57 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
27.7 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
CD48 Molecule
Function
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Biological Process
Defense response Source: ProtInc
Leukocyte migration Source: Reactome
Regulation of adaptive immune response Source: InterPro
Cellular Location
Cell membrane

Wang, Z., He, L., Li, W., Xu, C., Zhang, J., Wang, D., ... & Li, M. (2021). GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma. Journal for immunotherapy of cancer, 9(9).

Ziblat, A., Iraolagoitia, X. L. R., Nuñez, S. Y., Torres, N. I., Secchiari, F., Sierra, J. M., ... & Zwirner, N. W. (2021). Circulating and Tumor-Infiltrating NK Cells From Clear Cell Renal Cell Carcinoma Patients Exhibit a Predominantly Inhibitory Phenotype Characterized by Overexpression of CD85j, CD45, CD48 and PD-1. Frontiers in immunology, 12, 2143.

Wang, Z., Xie, C., Li, Y., Cai, J., Tang, J., Jian, J., ... & Lu, Y. (2020). Molecular characterization and expression of CD48 in Nile tilapia (Oreochromis niloticus) in response to different stimulus. Fish & shellfish immunology, 97, 515-522.

Martínez-Vicente, P., Farré, D., Engel, P., & Angulo, A. (2020). Divergent Traits and Ligand-Binding Properties of the Cytomegalovirus CD48 Gene Family. Viruses, 12(8), 813.

Wang, Z., Xiao, Y., Guan, W., Wang, M., Chen, J., Zhang, L., ... & Yu, L. (2020). Acute myeloid leukemia immune escape by epigenetic CD48 silencing. Clinical Science, 134(2), 261-271.

Zou, C., Zhu, C., Guan, G., Guo, Q., Liu, T., Shen, S., ... & Cheng, W. (2019). CD48 is a key molecule of immunomodulation affecting prognosis in glioma. OncoTargets and therapy, 12, 4181.

Pahima, H., Puzzovio, P. G., & Levi-Schaffer, F. (2019). 2B4 and CD48: A powerful couple of the immune system. Clinical Immunology, 204, 64-68.

Martinez-Vicente, P., Farré, D., Sánchez, C., Alcamí, A., Engel, P., & Angulo, A. (2019). Subversion of natural killer cell responses by a cytomegalovirus-encoded soluble CD48 decoy receptor. PLoS pathogens, 15(4), e1007658.

Huang, C. H., Liao, Y. J., Chiou, T. J., Huang, H. T., Lin, Y. H., & Twu, Y. C. (2019). TGF-β regulated leukemia cell susceptibility against NK targeting through the down-regulation of the CD48 expression. Immunobiology, 224(5), 649-658.

Liu, R., Wu, C., Li, L., Chi, F., Zhang, T., Xu, Y., ... & Wang, L. (2019). CD48 and α7 nicotinic acetylcholine receptor synergistically regulate fimH-mediated Escherichia coli K1 penetration and neutrophil transmigration across human brain microvascular endothelial cells. The Journal of infectious diseases, 219(3), 470-479.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CD48 protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY2888)

Human Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY2889)

Human Recombinant CD48 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2890)

Human Recombinant CD48 protein, His Tag (CAT#: V2LY-0526-LY2891)

Mouse Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY8037)

Mouse Recombinant CD48 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY8038)

Mouse Recombinant CD48 protein, His Tag (CAT#: V2LY-0526-LY8039)

Rat Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY9249)

Rat Recombinant CD48 protein, His Tag (CAT#: V2LY-0526-LY9250)

Rhesus Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY9686)

Related Products

Mouse Anti-CD48 Recombinant Antibody (CBYY-C0126) (CAT#: CBMAB-C0467-YY)

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Human Recombinant CD48 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2890)

Mouse Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY8037)

Mouse Anti-CD48 Recombinant Antibody (5-4.8) (CAT#: CBMAB-C3399-LY)

Rabbit Anti-CD48 Recombinant Antibody (001) (CAT#: CBMAB-C1453-LY)

Human Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY2889)

Mouse Recombinant CD48 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY8038)

Rat Recombinant CD48 protein, hFc Tag (CAT#: V2LY-0526-LY9249)

Human Anti-CD48 Recombinant Antibody (CBXC-0845) (CAT#: CBMAB-C1959-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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