Rat Mgp ELISA Kit (V2LY-0626-LY3077)

Go to compare Compare Online Inquiry
Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.101 ng/mL
Detection Range
0.2-70 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
12.0 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Matrix Gla Protein
Function
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Biological Process
Cartilage condensation Source: ProtInc
Cell differentiation Source: UniProtKB-KW
Ossification Source: ProtInc
Regulation of bone mineralization Source: InterPro
Cellular Location
Secreted
Involvement in disease
Keutel syndrome (KTLS):
An autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
PTM
Requires vitamin K-dependent gamma-carboxylation for its function.

Malhotra, R., Nicholson, C. J., Wang, D., Bhambhani, V., Paniagua, S., Slocum, C., ... & Ho, J. E. (2022). Matrix Gla protein levels are associated with arterial stiffness and incident heart failure with preserved ejection fraction. Arteriosclerosis, Thrombosis, and Vascular Biology, 42(2), e61-e73.

Du, T., Pan, L., Zheng, C., Chen, K., Yang, Y., Chen, J., ... & Sun, P. (2022). Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin. Breast Cancer Research, 24(1), 1-17.

Kumric, M., Borovac, J. A., Ticinovic Kurir, T., Martinovic, D., Frka Separovic, I., Baric, L., & Bozic, J. (2021). Role of Matrix Gla Protein in the complex network of coronary artery disease: a comprehensive review. Life, 11(8), 737.

Roumeliotis, S., Dounousi, E., Salmas, M., Eleftheriadis, T., & Liakopoulos, V. (2020). Vascular calcification in chronic kidney disease: the role of vitamin K-dependent matrix Gla protein. Frontiers in medicine, 7, 154.

Bjørklund, G., Svanberg, E., Dadar, M., Card, D. J., Chirumbolo, S., Harrington, D. J., & Aaseth, J. (2020). The role of matrix Gla protein (MGP) in vascular calcification. Current Medicinal Chemistry, 27(10), 1647-1660.

Li, C., Li, J., He, F., Li, K., Li, X., & Zhang, Y. (2020). Matrix Gla protein regulates adipogenesis and is serum marker of visceral adiposity. Adipocyte, 9(1), 68-76.

Roumeliotis, S., Dounousi, E., Eleftheriadis, T., & Liakopoulos, V. (2019). Association of the inactive circulating matrix Gla protein with vitamin K intake, calcification, mortality, and cardiovascular disease: a review. International journal of molecular sciences, 20(3), 628.

Wei, F. F., Trenson, S., Verhamme, P., Vermeer, C., & Staessen, J. A. (2019). Vitamin K–dependent matrix Gla protein as multifaceted protector of vascular and tissue integrity. Hypertension, 73(6), 1160-1169.

Shepherd, C., Reese, A. E., Reynard, L. N., & Loughlin, J. (2019). Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP. Arthritis research & therapy, 21(1), 1-9.

Zhang, J., Ma, Z., Yan, K., Wang, Y., Yang, Y., & Wu, X. (2019). Matrix Gla protein promotes the bone formation by up-regulating Wnt/β-catenin signaling pathway. Frontiers in Endocrinology, 10, 891.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Rat Mgp ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.