Rat Oxtr ELISA Kit (V2LY-0626-LY1687)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.11 ng/mL
Detection Range
0.2-60 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
42.9 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Oxytocin Receptor
Function
Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Biological Process
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Digestive tract developmentIEA:Ensembl
Eating behaviorIEA:Ensembl
ERK1 and ERK2 cascadeIEA:Ensembl
Estrous cycleIEA:Ensembl
Female pregnancyManual Assertion Based On ExperimentIBA:GO_Central
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Heart developmentIEA:Ensembl
LactationManual Assertion Based On ExperimentTAS:ProtInc
Maternal behaviorIEA:Ensembl
Maternal process involved in parturitionManual Assertion Based On ExperimentIBA:GO_Central
MemoryIEA:Ensembl
Muscle contractionManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of gastric acid secretionIEA:Ensembl
Positive regulation of blood pressureIEA:Ensembl
Positive regulation of cold-induced thermogenesisBy SimilarityISS:YuBioLab
Positive regulation of cytosolic calcium ion concentrationIEA:Ensembl
Positive regulation of norepinephrine secretionIEA:Ensembl
Positive regulation of penile erectionIEA:Ensembl
Positive regulation of synapse assemblyIEA:Ensembl
Positive regulation of synaptic transmission, GABAergicIEA:Ensembl
Positive regulation of synaptic transmission, glutamatergicIEA:Ensembl
Positive regulation of uterine smooth muscle contractionIEA:Ensembl
Positive regulation of vasoconstrictionManual Assertion Based On ExperimentIBA:GO_Central
Regulation of systemic arterial blood pressure by vasopressinManual Assertion Based On ExperimentIBA:GO_Central
Response to amphetamineIEA:Ensembl
Response to anoxiaIEA:Ensembl
Response to cocaineIEA:Ensembl
Response to cytokineIEA:Ensembl
Response to estradiolIEA:Ensembl
Response to peptide hormoneIEA:Ensembl
Response to progesteroneIEA:Ensembl
Response to xenobiotic stimulusIEA:Ensembl
SleepIEA:Ensembl
Social behaviorIEA:Ensembl
Sperm ejaculationIEA:Ensembl
Suckling behaviorIEA:Ensembl
Telencephalon developmentIEA:Ensembl
Topology
Extracellular: 1-38
Helical: 39-63
Cytoplasmic: 64-74
Helical: 75-97
Extracellular: 98-113
Helical: 114-135
Cytoplasmic: 136-154
Helical: 155-175
Extracellular: 176-202
Helical: 203-225
Cytoplasmic: 226-275
Helical: 276-294
Extracellular: 295-309
Helical: 310-332
Cytoplasmic: 333-389

Pierzynowska, K., Gaffke, L., Żabińska, M., Cyske, Z., Rintz, E., Wiśniewska, K., ... & Węgrzyn, G. (2023). Roles of the oxytocin receptor (OXTR) in human diseases. International journal of molecular sciences, 24(4), 3887.

Kohlhoff, J., Cibralic, S., Hawes, D. J., & Eapen, V. (2022). Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: A systematic narrative review. Neuroscience & Biobehavioral Reviews, 135, 104573.

Rokicki, J., Kaufmann, T., De Lange, A. M. G., van der Meer, D., Bahrami, S., Sartorius, A. M., ... & Quintana, D. S. (2022). Oxytocin receptor expression patterns in the human brain across development. Neuropsychopharmacology, 47(8), 1550-1560.

Moerkerke, M., Bonte, M. L., Daniels, N., Chubar, V., Alaerts, K., Steyaert, J., & Boets, B. (2021). Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits–A systematic review. Research in Autism Spectrum Disorders, 85, 101785.

Danoff, J. S., Wroblewski, K. L., Graves, A. J., Quinn, G. C., Perkeybile, A. M., Kenkel, W. M., ... & Connelly, J. J. (2021). Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression. Clinical epigenetics, 13, 1-16.

Zheng, S., Masuda, T., Matsunaga, M., Noguchi, Y., Ohtsubo, Y., Yamasue, H., & Ishii, K. (2020). Oxytocin receptor gene (OXTR) and childhood adversity influence trust. Psychoneuroendocrinology, 121, 104840.

Tops, S., Habel, U., & Radke, S. (2019). Genetic and epigenetic regulatory mechanisms of the oxytocin receptor gene (OXTR) and the (clinical) implications for social behavior. Hormones and behavior, 108, 84-93.

Kraaijenvanger, E. J., He, Y., Spencer, H., Smith, A. K., Bos, P. A., & Boks, M. P. (2019). Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies. Neuroscience & Biobehavioral Reviews, 96, 127-142.

Ebner, N. C., Lin, T., Muradoglu, M., Weir, D. H., Plasencia, G. M., Lillard, T. S., ... & Connelly, J. J. (2019). Associations between oxytocin receptor gene (OXTR) methylation, plasma oxytocin, and attachment across adulthood. International Journal of Psychophysiology, 136, 22-32.

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For research use only. Not intended for any clinical use.

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