Rat Sdc4 ELISA Kit (V2LY-0626-LY1798)

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Tested Data
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.052 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
22.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Syndecan 4
Function
Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Biological Process
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process inner ear receptor cell stereocilium organizationIEA:Ensembl
Biological Process negative regulation of T cell proliferationManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process neural tube closureIEA:Ensembl
Biological Process positive regulation of exosomal secretionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of extracellular exosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of focal adhesion assemblyIEA:Ensembl
Biological Process positive regulation of protein kinase activityIEA:Ensembl
Biological Process positive regulation of stress fiber assemblyIEA:Ensembl
Biological Process regulation of fibroblast migrationIEA:Ensembl
Biological Process ureteric bud developmentIEA:Ensembl
Biological Process wound healingIEA:Ensembl
Cellular Location
Isoform 1
Membrane
Secreted
Shedding of the ectodomain produces a soluble form.
Isoform 2
Secreted
Topology
Extracellular: 19-145
Helical: 146-170
Cytoplasmic: 171-198
PTM
Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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