Rhesus Recombinant IFNA2 protein (V2LY-0526-LY9757)

Name: Rhesus Recombinant IFNA2 protein
SKU: V2LY-0526-LY9757
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Yeast

Protein Species

Rhesus

Protein Construction

This product is Rhesus Recombinant IFNA2 protein consist of Amino Acid: 24-188 and predicts a molecular mass of 19.5 kDa.

Molecule Mass

19.5 kDa

Sequence

Amino Acid: 24-188

Species

Rhesus

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥80% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Interferon Alpha 2

Function

Produced by macrophages, IFN-alpha have antiviral activities.

Biological Process

Adaptive immune response Source: GO_Central
Apoptotic process Source: ProtInc
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cell-cell signaling Source: ProtInc
Cell surface receptor signaling pathway Source: ProtInc
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to virus Source: BHF-UCL
Humoral immune response Source: GO_Central
Inflammatory response Source: ProtInc
Natural killer cell activation involved in immune response Source: GO_Central
Negative regulation of gene expression Source: UniProtKB
Negative regulation of interleukin-13 production Source: UniProtKB
Negative regulation of interleukin-5 production Source: UniProtKB
Negative regulation of T cell differentiation Source: UniProtKB
Negative regulation of T-helper 2 cell cytokine production Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of viral entry into host cell Source: BHF-UCL
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Positive regulation of phosphorylation Source: AgBase
Positive regulation of transcription, DNA-templated Source: AgBase
Positive regulation of tyrosine phosphorylation of STAT protein Source: BHF-UCL
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central

Cellular Location

Secreted

Verkaaik, M., Javad, W. M., Qi, H., van Helden-Meeuwsen, C. G., Huijser, E., van den Berg, L., ... & Versnel, M. A. (2022). PO. 3.67 Measuring IFNA2 levels by a single-molecule array in clinical practice of childhood-onset sle patients does matter; results from a single center longitudinal study.

Wang, S., Chen, S. N., Sun, Z., Pang, A. N., Wang, S., Liu, L. H., ... & Nie, P. (2021). Four type I IFNs, IFNa1, IFNa2, IFNb, IFNc, and their receptor usage in an osteoglossomorph fish, the Asian arowana, Scleropages formosus. Fish & Shellfish Immunology, 117, 70-81.

Liu, X., Zhang, Y., Liang, H., Zhang, Y., & Xu, Y. (2020). MicroRNA-499-3p inhibits proliferation and promotes apoptosis of retinal cells in diabetic retinopathy through activation of the TLR4 signaling pathway by targeting IFNA2. Gene, 741, 144539.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Ifna2 ELISA Kit (CAT#: V2LY-0626-LY2443)

Human IFNA2 ELISA Kit (CAT#: V2LY-0626-LY3740)

IFNA2 Matched Antibody Pair (600) (CAT#: APMAB-600LY)

IFNA2 Matched Antibody Pair (601) (CAT#: APMAB-601LY)

IFNA2 Matched Antibody Pair (602) (CAT#: APMAB-602LY)

IFNA2 Matched Antibody Pair (603) (CAT#: APMAB-603LY)

Mouse Recombinant IFNA2 protein (CAT#: V2LY-0526-LY8563)

Mouse Recombinant IFNA2 protein, hFc Tag (CAT#: V2LY-0526-LY8564)

Rhesus Recombinant IFNA2 protein, His Tag (CAT#: V2LY-0526-LY9758)

Rhesus Recombinant IFNA2 protein, Fc Tag (CAT#: V2LY-0526-LY9759)

Antibody Pairs

IFNA2 Matched Antibody Pair (600) (CAT#: APMAB-600LY)

IFNA2 Matched Antibody Pair (601) (CAT#: APMAB-601LY)

IFNA2 Matched Antibody Pair (602) (CAT#: APMAB-602LY)

IFNA2 Matched Antibody Pair (603) (CAT#: APMAB-603LY)

Related Products

Rat Anti-IFNA2 Recombinant Antibody (F18) (CAT#: CBMAB-I0269-YY)

Human Recombinant IFNA2 (2B) protein, hFc Tag (CAT#: V2LY-0526-LY5037)

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0097) (CAT#: CBMAB-I0266-YY)

Mouse Anti-IFNA2 Recombinant Antibody (2E5) (CAT#: CBMAB-A4252-LY)

Mouse Anti-IFNA2 Recombinant Antibody (KT5) (CAT#: CBMAB-I0794-YY)

Mouse Anti-IFNA2 Recombinant Antibody (CBYY-I0765) (CAT#: CBMAB-I1700-YY)

Mouse Recombinant IFNA2 protein, hFc Tag (CAT#: V2LY-0526-LY8564)

Human Recombinant IFNA2 (2B) protein (CAT#: V2LY-0526-LY5036)

Mouse Ifna2 ELISA Kit (CAT#: V2LY-0626-LY2443)

IFNA2 Matched Antibody Pair (603) (CAT#: APMAB-603LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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