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SHMT1 Matched Antibody Pair (1094) (APMAB-1094LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-SHMT1 monoclonal antibody, 100 ug
Detection Antibody
Anti-SHMT1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Alternative Names
Serine Hydroxymethyltransferase 1; Cytoplasmic Serine Hydroxymethyltransferase; Serine Hydroxymethyltransferase 1 (Soluble); Glycine Hydroxymethyltransferase; Serine Methylase; EC 2.1.2.1;
Entrez Gene ID
6470
UniProt ID
P34896
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For research use only. Not intended for any clinical use.

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