ACBD3
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq]
Full Name
acyl-Coenzyme A binding domain containing 3
Function
Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase.
Biological Process
Post-Golgi vesicle-mediated transport
Steroid biosynthetic process
Viral process
Steroid biosynthetic process
Viral process
Cellular Location
Golgi apparatus membrane; Mitochondrion. Also mitochondrial (via its interaction with PBR).
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Anti-ACBD3 antibodies
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Target: ACBD3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-179238
Application*: E, WB
Target: ACBD3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-179237
Application*: E, IF, WB
Target: ACBD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-84738
Application*: F
Target: ACBD3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: V2-84737
Application*: E, WB
Target: ACBD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-84734
Application*: F
Target: ACBD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-84733
Application*: E, IC, IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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