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AEBP2

DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates Lys-9 and Lys-27 residues of histone H3.
Full Name
AE Binding Protein 2
Function
Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex.
Biological Process
Chromatin organization
Negative regulation of gene expression, epigenetic
Regulation of transcription by RNA polymerase II
Cellular Location
Nucleus. Localizes to chromatin as part of the PRC2 complex.
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Anti-AEBP2 antibodies

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Mouse Anti-AEBP2 Recombinant Antibody (CBT4128) (V2LY-0625-LY619)

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Target: AEBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4128
Application*: WB, IC, F
Datasheet SDS

Mouse Anti-AEBP2 Recombinant Antibody (CBT3757) (V2LY-0625-LY618)

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Target: AEBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3757
Application*: WB, IC
Datasheet SDS

Mouse Anti-AEBP2 Recombinant Antibody (V2-180038) (CBMAB-A1444-YC)

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Target: AEBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-180038
Application*: WB, E, IF
Datasheet SDS

Rabbit Anti-AEBP2 Recombinant Antibody (V2-180037) (CBMAB-A1443-YC)

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Target: AEBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: V2-180037
Application*: WB, IP
Datasheet SDS

Mouse Anti-AEBP2 Recombinant Antibody (V2-180036) (CBMAB-A1442-YC)

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Target: AEBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-180036
Application*: WB, E, F
Datasheet SDS

Mouse Anti-AEBP2 Recombinant Antibody (V2-180035) (CBMAB-A1441-YC)

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Target: AEBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: V2-180035
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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