AEBP2

DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates Lys-9 and Lys-27 residues of histone H3.

Full Name

AE Binding Protein 2

Function

Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex.

Biological Process

Chromatin organization
Negative regulation of gene expression, epigenetic
Regulation of transcription by RNA polymerase II

Cellular Location

Nucleus. Localizes to chromatin as part of the PRC2 complex.

Anti-AEBP2 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-AEBP2 Recombinant Antibody (V2-180038) (CBMAB-A1444-YC)

Datasheet

SDS

Target: AEBP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-180038

Application*: WB, E, IF

Rabbit Anti-AEBP2 Recombinant Antibody (V2-180037) (CBMAB-A1443-YC)

Datasheet

SDS

Target: AEBP2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: V2-180037

Application*: WB, IP

Mouse Anti-AEBP2 Recombinant Antibody (V2-180036) (CBMAB-A1442-YC)

Datasheet

SDS

Target: AEBP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-180036

Application*: WB, E, F

Mouse Anti-AEBP2 Recombinant Antibody (V2-180035) (CBMAB-A1441-YC)

Datasheet

SDS

Target: AEBP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Pig

Clone: V2-180035

Application*: E, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)