AHCTF1

Full Name

AT-Hook Containing Transcription Factor 1

Function

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

Biological Process

Cell division
Mitotic nuclear envelope reassembly
Mitotic spindle organization
mRNA transport
Nuclear pore complex assembly
Protein transport
Regulation of cytokinesis

Cellular Location

Cytoplasm; Nucleus; Nucleus envelope; Nucleus matrix; Nucleoplasm; Nuclear pore complex; kinetochore. Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.

Anti-AHCTF1 antibodies

Mouse Anti-AHCTF1 Recombinant Antibody (V2-180261) (CBMAB-A1694-YC)

Datasheet

SDS

Target: AHCTF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-180261

Application*: WB

Mouse Anti-AHCTF1 Recombinant Antibody (V2-180260) (CBMAB-A1693-YC)

Datasheet

SDS

Target: AHCTF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-180260

Application*: WB, IP

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)