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AHCTF1

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required f

Full Name

AT-Hook Containing Transcription Factor 1

Function

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

Biological Process

Cell division
Mitotic nuclear envelope reassembly
Mitotic spindle organization
mRNA transport
Nuclear pore complex assembly
Protein transport
Regulation of cytokinesis

Cellular Location

Cytoplasm; Nucleus; Nucleus envelope; Nucleus matrix; Nucleoplasm; Nuclear pore complex; kinetochore. Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.

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Anti-AHCTF1 antibodies

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Mouse Anti-AHCTF1 Recombinant Antibody (V2-180261) (CBMAB-A1694-YC)

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Target: AHCTF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-180261

Application*: WB

Mouse Anti-AHCTF1 Recombinant Antibody (V2-180260) (CBMAB-A1693-YC)

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Target: AHCTF1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-180260

Application*: WB, IP

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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