AHSA1

Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360).
Full Name
Activator Of HSP90 ATPase Activity 1
Function
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155).
Biological Process
Positive regulation of ATPase activity
Protein folding
Viral process
Cellular Location
Cytosol; Endoplasmic reticulum. May transiently interact with the endoplasmic reticulum.
PTM
Phosphorylation at Tyr-223 enhances binding to chaperone HSP90AA1.
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Anti-AHSA1 antibodies

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Rat Anti-AHSA1 Recombinant Antibody (V2-634176) (CBMAB-AP211LY)

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Target: AHSA1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: V2-634176
Application*: ICC/IF, ELISA, IHC, IP, WB
Datasheet SDS

Mouse Anti-AHSA1 Recombinant Antibody (V2-634175) (CBMAB-AP210LY)

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Target: AHSA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: V2-634175
Application*: ICC/IF, ELISA, WB
Datasheet SDS

Rat Anti-AHSA1 Recombinant Antibody (V2-634174) (CBMAB-AP209LY)

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Target: AHSA1
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: V2-634174
Application*: ICC/IF, ELISA, IHC, IP, WB
Datasheet SDS

Mouse Anti-AHSA1 Recombinant Antibody (V2-611053) (CBMAB-A0206-LY)

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Target: AHSA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-611053
Application*: WB, E
Datasheet SDS

AHSA1 Matched Antibody Pair (037) (APMAB-037LY)

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Target: AHSA1
Specificity: Human
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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