ALDH1A1

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
Full Name
Aldehyde Dehydrogenase 1 Family Member A1
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (PubMed:19296407, PubMed:26373694, PubMed:25450233).
Biological Process
Cellular aldehyde metabolic process Source: ProtInc
Ethanol oxidation Source: Reactome
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate Source: Reactome
Negative regulation of cold-induced thermogenesis Source: YuBioLab
Retinoid metabolic process Source: UniProtKB
Retinol metabolic process Source: UniProtKB-UniPathway
Cellular Location
Cytosol
PTM
The N-terminus is blocked most probably by acetylation.
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Anti-ALDH1A1 antibodies

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Mouse Anti-ALDH1A1 Recombinant Antibody (CBT4281) (V2LY-0625-LY675)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4281
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (CBT2254) (V2LY-0625-LY674)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2254
Application*: WB, IH
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (CBT149) (V2LY-0625-LY3760)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT149
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (CBT3847) (V2LY-0625-LY2530)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3847
Application*: WB, IH
Datasheet SDS

ALDH1A1 Matched Antibody Pair (062) (APMAB-062LY)

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Target: ALDH1A1
Specificity: Human
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (5G9E6C9) (CBMAB-A2254-YC)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5G9E6C9
Application*: WB, E, FC, IC
Datasheet SDS

Rabbit Anti-ALDH1A1 Recombinant Antibody (D9J7R) (CBMAB-A2250-YC)

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Target: ALDH1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D9J7R
Application*: FC, IC, IF, IP, WB
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (5A11) (CBMAB-A2246-YC)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5A11
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (1G6) (CBMAB-A2245-YC)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1G6
Application*: E, P, IP, WB
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (A6) (CBMAB-A2241-YC)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A6
Application*: E, IC, IF, WB
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (H4) (CBMAB-A2240-YC)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: H4
Application*: E, IC, IF, IH, WB
Datasheet SDS

Rabbit Anti-ALDH1A1 Recombinant Antibody (23) (CBMAB-0052CQ)

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Target: ALDH1A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 23
Application*: E
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (B5) (CBMAB-0051CQ)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: B5
Application*: E, IC, IF, IH, WB, IP
Datasheet SDS

Mouse Anti-ALDH1A1 Recombinant Antibody (ALDH1A1/1381) (CBMAB-0050CQ)

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Target: ALDH1A1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: ALDH1A1/1381
Application*: WB, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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