ALPI
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]
Full Name
Alkaline Phosphatase, Intestinal
Biological Process
Dephosphorylation Source: UniProtKB
Digestion Source: Reactome
Phosphatidic acid biosynthetic process Source: Reactome
Digestion Source: Reactome
Phosphatidic acid biosynthetic process Source: Reactome
Cellular Location
Cell membrane
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Anti-ALPI antibodies
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Target: ALPI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle
Clone: P4A10E4
Application*: E, IH, IP
Target: ALPI
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Cattle
Clone: AP1B9
Application*: IF
Target: ALPI
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: AAP1
Application*: E
Target: ALPI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B10E7
Application*: E, F, WB
Target: ALPI
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A8
Application*: E, WB
Target: ALPI
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 01
Application*: E
Target: ALPI
Sensitivity: 0.02 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Cattle
Assay Type: Sandwich
Reactivity: Cattle
Target: ALPI
Sensitivity: 0.55 ng/mL
Detection Range: 1-400 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: ALPI
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-503
Tag: His Tag
Target: ALPI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3334
Application*: F
Target: ALPI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4247
Application*: WB, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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