ALPK2
Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation.
Full Name
Alpha Kinase 2
Function
Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752).
Biological Process
Cardiac muscle cell development Source: UniProtKB
Epicardium morphogenesis Source: UniProtKB
Establishment of cell polarity Source: UniProtKB
Heart morphogenesis Source: UniProtKB
Negative regulation of Wnt signaling pathway involved in heart development Source: UniProtKB
Regulation of apoptotic process Source: UniProtKB
Regulation of gene expression Source: UniProtKB
Epicardium morphogenesis Source: UniProtKB
Establishment of cell polarity Source: UniProtKB
Heart morphogenesis Source: UniProtKB
Negative regulation of Wnt signaling pathway involved in heart development Source: UniProtKB
Regulation of apoptotic process Source: UniProtKB
Regulation of gene expression Source: UniProtKB
Cellular Location
Basolateral cell membrane
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Anti-ALPK2 antibodies
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Target: ALPK2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B5
Application*: E, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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