BRS3

The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]

Full Name

Bombesin Receptor Subtype 3

Function

Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Biological Process

Adult feeding behavior Source: ProtInc
Glucose metabolic process Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Regulation of blood pressure Source: ProtInc

Cellular Location

Cell membrane

Topology

Extracellular: 1-41 aa
Helical: 42-63 aa
Cytoplasmic: 64-82 aa
Helical: 83-103 aa
Extracellular: 104-121 aa
Helical: 122-143 aa
Cytoplasmic: 144-163 aa
Helical: 164-184 aa
Extracellular: 185-220 aa
Helical: 221-241 aa
Cytoplasmic: 242-272 aa
Helical: 273-293 aa
Extracellular: 294-313 aa
Helical: 314-333 aa
Cytoplasmic: 334-399 aa

Anti-BRS3 antibodies

Mouse Anti-BRS3 Recombinant Antibody (EG417) (CBMAB-EN475-LY)

Datasheet

SDS

Target: BRS3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: EG417

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)