BRS3

The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]

Full Name

Bombesin Receptor Subtype 3

Function

Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Biological Process

Adult feeding behavior Source: ProtInc
Glucose metabolic process Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Regulation of blood pressure Source: ProtInc

Cellular Location

Cell membrane

Topology

Extracellular: 1-41 aa
Helical: 42-63 aa
Cytoplasmic: 64-82 aa
Helical: 83-103 aa
Extracellular: 104-121 aa
Helical: 122-143 aa
Cytoplasmic: 144-163 aa
Helical: 164-184 aa
Extracellular: 185-220 aa
Helical: 221-241 aa
Cytoplasmic: 242-272 aa
Helical: 273-293 aa
Extracellular: 294-313 aa
Helical: 314-333 aa
Cytoplasmic: 334-399 aa