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CALU

The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Full Name

Calumenin

Function

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).

Biological Process

Cellular protein metabolic process Source: Reactome
Post-translational protein modification Source: Reactome

Cellular Location

Golgi apparatus; Secreted; Endoplasmic reticulum membrane; Melanosome; Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

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Anti-CALU antibodies

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Mouse Anti-CALU Recombinant Antibody (CBCNC-141) (CBMAB-C1260-CN)

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Target: CALU

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CBCNC-141

Application*: WB

Mouse Anti-CALU Recombinant Antibody (CBYY-C0903) (CBMAB-C2340-YY)

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Target: CALU

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CBYY-C0903

Application*: WB

Mouse Anti-CALU Recombinant Antibody (CBYY-C0902) (CBMAB-C2339-YY)

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Target: CALU

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat

Clone: CBYY-C0902

Application*: E, WB, IF, P, IP

Mouse Anti-CALU Recombinant Antibody (6C8) (CBMAB-C8133-LY)

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Target: CALU

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 6C8

Application*: E, WB

Human Recombinant CALU protein, His Tag (V2LY-0526-LY2524)

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Target: CALU

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-311

Tag: His Tag

Mouse Anti-CALU Recombinant Antibody (
26H10) (V2LY-0725-LY278)

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Target: CALU

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: 26H10

Application*: E, WB

Mouse Anti-CALU Recombinant Antibody (4C6) (CBMAB-CP0083-LY)

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Target: CALU

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Monkey

Clone: 4C6

Application*: WB, IF

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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