CCL27
CCL27 (C-C Motif Chemokine Ligand 27) is a Protein Coding gene. Diseases associated with CCL27 include Dermatitis and Dermatitis, Atopic. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity. An important paralog of this gene is CCL28.
Full Name
C-C Motif Chemokine Ligand 27
Function
Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: ProtInc
Killing of cells of other organism Source: UniProtKB
Positive regulation of actin cytoskeleton reorganization Source: GO_Central
Positive regulation of T cell chemotaxis Source: GO_Central
Cell-cell signaling Source: ProtInc
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: ProtInc
Killing of cells of other organism Source: UniProtKB
Positive regulation of actin cytoskeleton reorganization Source: GO_Central
Positive regulation of T cell chemotaxis Source: GO_Central
Cellular Location
Secreted
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Anti-CCL27 antibodies
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Target: CCL27
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYY-C1082
Application*: WB, IF, F
Target: CCL27
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0978
Application*: E
Target: CCL27
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0977
Application*: WB, IH, N
Target: CCL27
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-0975
Application*: IF, WB, E, IP
Target: CCL27
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0974
Application*: E
Target: CCL27
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 6M35
Application*: WB, P, N
Target: CCL27
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 124302
Application*: E, IH
Target: CCL27
Sensitivity: 0.047 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Ccl27
Sensitivity: 0.004 ng/mL
Detection Range: 0.007-1.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CCL27
Expressed Host: E. coli
Sequence: Amino Acid: 25-112
Tag: His Tag
Target: CCL27
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2427
Application*: IH, IC, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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