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CD1B

CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Mycobacterium Tuberculosis 1. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1A.
Full Name
CD1b Molecule
Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: GO_Central
Antigen processing and presentation, exogenous lipid antigen via MHC class Ib Source: GO_Central
Positive regulation of T cell mediated cytotoxicity Source: GO_Central
Regulation of immune response Source: Reactome
Cellular Location
Lysosome membrane; Endosome membrane; Cell membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Topology
Extracellular: 18-303
Helical: 304-324
Cytoplasmic: 325-333
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Anti-CD1B antibodies

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Mouse Anti-CD1B Recombinant Antibody (CBT2377) (V2LY-0625-LY886)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2377
Application*: F
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (CBT2457) (V2LY-0625-LY885)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2457
Application*: F
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (MT-101) (CBMAB-C10043-LY)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: MT-101
Application*: F, IP, IF
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (CBXC-0182) (CBMAB-C4795-CQ)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgM
Specificity: Sheep, Cattle, Goat
Clone: CBXC-0182
Application*: F, IF, IP, WB
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (CBXC-0181) (CBMAB-C4794-CQ)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Sheep, Cattle
Clone: CBXC-0181
Application*: F
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (CBXC-1308) (CBMAB-C1575-CQ)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-1308
Application*: E
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (SN13) (CBMAB-C1036-CQ)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: SN13
Application*: F, IH, IP
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (CBXC-2336) (CBMAB-C0003-CQ)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Dog, Cattle, Goat, Horse
Clone: CBXC-2336
Application*: F, IH, IP
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (CBYY-C0638) (CBMAB-C1928-YY)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Sheep, Cattle, Goat
Clone: CBYY-C0638
Application*: F, IP, IF
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (2E4) (CBMAB-C4997-LY)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E4
Application*: E
Datasheet SDS

Mouse Anti-CD1B Recombinant Antibody (O249) (CBMAB-C0120-LY)

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Target: CD1B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: O249
Application*: F, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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