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CD5

CD5 (CD5 Molecule) is a Protein Coding gene. Diseases associated with CD5 include Thymus Cancer and Richter's Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and B Cell Development Pathways. Gene Ontology (GO) annotations related to this gene include receptor activity and scavenger receptor activity.

Full Name

CD5 Molecule

Alternative Names

CD5 Molecule; Lymphocyte Antigen T1/Leu-1; CD5 Antigen (P56-62); LEU1; T-Cell Surface Glycoprotein CD5; CD5 Antigen; T1;

Function

May act as a receptor in regulating T-cell proliferation.

Biological Process

Apoptotic signaling pathway Source: Ensembl
Cell recognition Source: UniProtKB
T cell costimulation Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 25-372
Helical: 373-402
Cytoplasmic: 403-495

PTM

Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.

Anti-CD5 antibodies

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-CD5 Recombinant Antibody (AG35) (V2LY-0524-LY31)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: AG35

Application*: F, C, In Vivo

Mouse Anti-CD5 Recombinant Antibody (EC112) (V2LY-0624-LY112)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EC112

Application*: P, IF

Rat Anti-CD5 Recombinant Antibody (CBXC-1649) (CBMAB-C2933-CQ)

SDS

Target: CD5

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBXC-1649

Application*: F, IH, IP, IF

Rat Anti-CD5 Recombinant Antibody (CBXC-1387) (CBMAB-C2616-CQ)

SDS

Target: CD5

Host: Rat

Antibody Isotype: IgG2a

Specificity: Dog

Clone: CBXC-1387

Application*: F, IP, IH

Mouse Anti-CD5 Recombinant Antibody (UCHT2) (CBMAB-C1160-CQ)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: UCHT2

Application*: IF, IP, WB, F, P

Mouse Anti-CD5 Recombinant Antibody (CBFYC-0538) (CBMAB-C0591-FY)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat, Horse, Cattle, Rabbit

Clone: CBFYC-0538

Application*: WB, IP, IF, P

Mouse Anti-CD5 Recombinant Antibody (CBFYC-0536) (CBMAB-C0589-FY)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0536

Application*: F, IP, IF

Mouse Anti-CD5 Recombinant Antibody (CBFYC-0445) (CBMAB-C0491-FY)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYC-0445

Application*: WB, IP, IF

Mouse Anti-CD5 Recombinant Antibody (CBFYC-0429) (CBMAB-C0475-FY)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYC-0429

Application*: WB, IP, IF, F

Rabbit Anti-CD5 Recombinant Antibody (CBFYC-0211) (CBMAB-C0237-FY)

SDS

Target: CD5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBFYC-0211

Application*: F

Mouse Anti-CD5 Recombinant Antibody (CBFYC-0164) (CBMAB-C0187-FY)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYC-0164

Application*: WB, IP, IF, F

Mouse Anti-CD5 Recombinant Antibody (CBFYC-0104) (CBMAB-C0121-FY)

SDS

Target: CD5

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Cattle

Clone: CBFYC-0104

Application*: WB, IP, IF, F

Rabbit Anti-CD5 Recombinant Antibody (CBFYC-0052) (CBMAB-C0059-FY)

SDS

Target: CD5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYC-0052

Application*: WB

Rabbit Anti-CD5 Recombinant Antibody (006) (CBMAB-C1532-LY)

SDS

Target: CD5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Rat

Clone: 006

Application*: E

Rabbit Anti-CD5 Recombinant Antibody (114) (CBMAB-C0208-LY)

SDS

Target: CD5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: 114

Application*: F, IF

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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