CELA3B

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009]
Full Name
Chymotrypsin Like Elastase Family Member 3B
Function
Efficient protease with alanine specificity but only little elastolytic activity.
Biological Process
Proteolysis Source: GO_Central
Cellular Location
Extracellular space
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Anti-CELA3B antibodies

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Mouse Anti-CELA3B Recombinant Antibody (CBWJC-2467) (CBMAB-C3536WJ)

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Target: CELA3B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJC-2467
Application*: E, WB
Datasheet SDS

Mouse Anti-CELA3B Recombinant Antibody (2H6) (CBMAB-C13091-LY)

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Target: CELA3B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2H6
Application*: E
Datasheet SDS

Mouse Anti-CELA3B Recombinant Antibody (C4185) (CBMAB-C4185-CQ)

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Target: CELA3B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: C4185
Application*: E, IH
Datasheet SDS

Rabbit Anti-CELA3B Recombinant Antibody (C4184) (CBMAB-C4184-CQ)

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Target: CELA3B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: C4184
Application*: IH
Datasheet SDS

Rabbit Anti-CELA3B Recombinant Antibody (CBXC-0362) (CBMAB-C3193-CQ)

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Target: CELA3B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-0362
Application*: IH
Datasheet SDS

Mouse Anti-CELA3B Recombinant Antibody (CBFYE-0337) (CBMAB-E0629-FY)

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Target: CELA3B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-0337
Application*: WB, E, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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