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CGN

CGN (Cingulin) is a Protein Coding gene. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways and Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer. Gene Ontology (GO) annotations related to this gene include actin binding and motor activity. An important paralog of this gene is CGNL1.

Full Name

CINGULIN

Function

Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.

Biological Process

Transforming growth factor beta receptor signaling pathway Source: Reactome

Cellular Location

Tight junction. Localizes to the apical junction complex composed of tight and adherens junctions (By similarity). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:12023291).

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Anti-CGN antibodies

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Mouse Anti-CGN Recombinant Antibody (C3388) (CBMAB-C3388-LY)

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Target: CGN

Host: Mouse

Antibody Isotype: IgM

Specificity: Cattle, Human, Mouse, Frog

Clone: C3388

Application*: IH, WB

Mouse Anti-CGN Recombinant Antibody (CBFYC-1791) (CBMAB-C1853-FY)

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Target: CGN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Dog, Human

Clone: CBFYC-1791

Application*: WB, IP, IF, E, P

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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