CLTB

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Full Name
Clathrin Light Chain B
Function
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Biological Process
Clathrin coat assembly Source: GO_Central
Clathrin-dependent endocytosis Source: GO_Central
Intracellular protein transport Source: InterPro
Membrane organization Source: Reactome
Cellular Location
Cytoplasmic vesicle membrane; Coated pit. Cytoplasmic face of coated pits and vesicles.
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Anti-CLTB antibodies

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Target: CLTB
Sensitivity: 0.051 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Cltb
Sensitivity: 0.106 ng/mL
Detection Range: 0.2-60 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CLTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Zebrafish
Clone: CBCNC-029
Application*: IF, IH, WB, IP
Target: CLTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBWJC-2824
Application*: IF, IH, WB
Target: CLTB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-2688
Application*: E, WB
Target: CLTB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4B12-1E3
Application*: WB, IH, IF, E
Target: CLTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLNC-201
Application*: WB, IP, IF, E, P
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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