CLTB
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Full Name
Clathrin Light Chain B
Function
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Biological Process
Clathrin coat assembly Source: GO_Central
Clathrin-dependent endocytosis Source: GO_Central
Intracellular protein transport Source: InterPro
Membrane organization Source: Reactome
Clathrin-dependent endocytosis Source: GO_Central
Intracellular protein transport Source: InterPro
Membrane organization Source: Reactome
Cellular Location
Cytoplasmic vesicle membrane; Coated pit. Cytoplasmic face of coated pits and vesicles.
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Anti-CLTB antibodies
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Target: CLTB
Sensitivity: 0.051 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Cltb
Sensitivity: 0.106 ng/mL
Detection Range: 0.2-60 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CLTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Zebrafish
Clone: CBCNC-029
Application*: IF, IH, WB, IP
Target: CLTB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBWJC-2824
Application*: IF, IH, WB
Target: CLTB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-2688
Application*: E, WB
Target: CLTB
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4B12-1E3
Application*: WB, IH, IF, E
Target: CLTB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLNC-201
Application*: WB, IP, IF, E, P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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