CTSH

CTSH (Cathepsin H) is a Protein Coding gene. Diseases associated with CTSH include Thyroid Crisis and Intermittent Explosive Disorder. Among its related pathways are Innate Immune System and Surfactant metabolism. Gene Ontology (GO) annotations related to this gene include protein complex binding and peptidase activity. An important paralog of this gene is CTSK.
Full Name
Cathepsin H
Function
Important for the overall degradation of proteins in lysosomes.
Biological Process
Adaptive immune response Source: UniProtKB
Antigen processing and presentation Source: UniProtKB
Bradykinin catabolic process Source: UniProtKB
Cellular protein metabolic process Source: Reactome
Cellular response to thyroid hormone stimulus Source: UniProtKB
Dichotomous subdivision of terminal units involved in lung branching Source: UniProtKB
ERK1 and ERK2 cascade Source: UniProtKB
Immune response-regulating signaling pathway Source: UniProtKB
Membrane protein proteolysis Source: UniProtKB
Metanephros development Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Neuropeptide catabolic process Source: UniProtKB
Neutrophil degranulation Source: Reactome
Positive regulation of angiogenesis Source: UniProtKB
Positive regulation of cell migration Source: UniProtKB
Positive regulation of cell population proliferation Source: UniProtKB
Positive regulation of epithelial cell migration Source: UniProtKB
Positive regulation of gene expression Source: UniProtKB
Positive regulation of peptidase activity Source: UniProtKB
Protein destabilization Source: UniProtKB
Proteolysis Source: UniProtKB
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Response to retinoic acid Source: UniProtKB
Surfactant homeostasis Source: UniProtKB
T cell mediated cytotoxicity Source: UniProtKB
Zymogen activation Source: UniProtKB
Cellular Location
Lysosome
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Anti-CTSH antibodies

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Rabbit Anti-CTSH Recombinant Antibody (CBWJC-3426) (V2LY-0125-LY443)

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Target: CTSH
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBWJC-3426
Application*: WB, E
Datasheet SDS

Mouse Anti-CTSH Recombinant Antibody (CBWJC-3424) (V2LY-0125-LY442)

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Target: CTSH
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJC-3424
Application*: WB, IP, E
Datasheet SDS

Mouse Anti-CTSH Recombinant Antibody (CBYY-C2319) (V2LY-0125-LY440)

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Target: CTSH
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C2319
Application*: WB
Datasheet SDS

Rat Anti-CTSH Recombinant Antibody (CBFYC-2450) (V2LY-0125-LY439)

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Target: CTSH
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2450
Application*: WB
Datasheet SDS

Rat Anti-CTSH Recombinant Antibody (C3421) (V2LY-0125-LY438)

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Target: CTSH
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: C3421
Application*: WB, IH
Datasheet SDS

Rabbit Anti-CTSH Recombinant Antibody (1490) (V2LY-0125-LY437)

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Target: CTSH
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 1490
Application*: IF, WB
Datasheet SDS

Mouse Anti-CTSH Recombinant Antibody (CBXC-0618) (CBMAB-C4229-CQ)

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Target: CTSH
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXC-0618
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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