CXCL13

CXCL13 (C-X-C Motif Chemokine Ligand 13) is a protein coding gene. Diseases associated with CXCL13 include Angioimmunoblastic T-Cell Lymphoma and Burkitt Lymphoma. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology annotations related to this gene include protein heterodimerization activity and chemokine activity.

C-X-C Motif Chemokine Ligand 13

Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.

Activation of GTPase activity Source: BHF-UCL
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
B cell chemotaxis Source: BHF-UCL
Cell-cell signaling Source: BHF-UCL
Cell surface receptor signaling pathway Source: BHF-UCL
Cellular response to lipopolysaccharide Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chronic inflammatory response Source: BHF-UCL
Defense response to bacterium Source: BHF-UCL
Endothelial cell chemotaxis to fibroblast growth factor Source: BHF-UCL
Germinal center formation Source: BHF-UCL
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: BHF-UCL
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis across high endothelial venule Source: BHF-UCL
Negative regulation of endothelial cell chemotaxis to fibroblast growth factor Source: BHF-UCL
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cell-cell adhesion mediated by integrin Source: BHF-UCL
Positive regulation of cytosolic calcium ion concentration Source: BHF-UCL
Positive regulation of integrin activation Source: BHF-UCL
Positive regulation of T cell chemotaxis Source: BHF-UCL
Regulation of angiogenesis Source: BHF-UCL
Regulation of humoral immune response Source: BHF-UCL

Secreted