CXCL13

CXCL13 (C-X-C Motif Chemokine Ligand 13) is a protein coding gene. Diseases associated with CXCL13 include Angioimmunoblastic T-Cell Lymphoma and Burkitt Lymphoma. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology annotations related to this gene include protein heterodimerization activity and chemokine activity.
Full Name
C-X-C Motif Chemokine Ligand 13
Function
Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.
Biological Process
Activation of GTPase activity Source: BHF-UCL
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
B cell chemotaxis Source: BHF-UCL
Cell-cell signaling Source: BHF-UCL
Cell surface receptor signaling pathway Source: BHF-UCL
Cellular response to lipopolysaccharide Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chronic inflammatory response Source: BHF-UCL
Defense response to bacterium Source: BHF-UCL
Endothelial cell chemotaxis to fibroblast growth factor Source: BHF-UCL
Germinal center formation Source: BHF-UCL
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: BHF-UCL
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis across high endothelial venule Source: BHF-UCL
Negative regulation of endothelial cell chemotaxis to fibroblast growth factor Source: BHF-UCL
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cell-cell adhesion mediated by integrin Source: BHF-UCL
Positive regulation of cytosolic calcium ion concentration Source: BHF-UCL
Positive regulation of integrin activation Source: BHF-UCL
Positive regulation of T cell chemotaxis Source: BHF-UCL
Regulation of angiogenesis Source: BHF-UCL
Regulation of humoral immune response Source: BHF-UCL
Cellular Location
Secreted
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Anti-CXCL13 antibodies

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Rat Anti-CXCL13 Recombinant Antibody (C11362) (CBMAB-C11362-LY)

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Target: CXCL13
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: C11362
Application*: N
Functional Assay
Datasheet SDS

Rat Anti-CXCL13 Recombinant Antibody (C0330) (CBMAB-C0330-LY)

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Target: CXCL13
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: C0330
Application*: WB, N, P
Functional Assay
Datasheet SDS

Mouse Cxcl13 ELISA Kit (V2LY-0626-LY3281)

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Target: Cxcl13
Sensitivity: 0.021 ng/mL
Detection Range: 0.05-20 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Human Recombinant CXCL13 protein (V2LY-0526-LY2302)

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Target: CXCL13
Expressed Host: E. coli
Sequence: Amino Acid: 23-94
Datasheet SDS

Cynomolgus Recombinant BCA-1/CXCL13 protein, His Tag (V2LY-0526-LY1391)

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Target: CXCL13
Expressed Host: E. coli
Sequence: Amino Acid: 23-109
Tag: His Tag
Datasheet SDS

Canine Recombinant CXCL13 protein, His Tag (V2LY-0526-LY1206)

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Target: CXCL13
Expressed Host: E. coli
Sequence: Amino Acid: 23-110
Tag: His Tag
Datasheet SDS

Mouse Anti-CXCL13 Recombinant Antibody (MA076) (V2LY-0125-LY667)

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Target: CXCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: MA076
Application*: N, WB, E, F
Functional Assay
Datasheet SDS

Mouse Anti-CXCL13 Recombinant Antibody (C11363) (V2LY-0125-LY666)

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Target: CXCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C11363
Application*: WB, B, IH, F
Datasheet SDS

Mouse Anti-CXCL13 Recombinant Antibody (14L309) (V2LY-0125-LY664)

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Target: CXCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L309
Application*: N, IH, F
Functional Assay
Datasheet SDS

Mouse Anti-CXCL13 Recombinant Antibody (CBXC-1241) (V2LY-0125-LY663)

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Target: CXCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1241
Application*: E, WB, F
Datasheet SDS

Rabbit Anti-CXCL13 Recombinant Antibody (CBXC-1493) (V2LY-0125-LY662)

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Target: CXCL13
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1493
Application*: WB
Datasheet SDS

Rat Anti-CXCL13 Recombinant Antibody (CBFYC-2503) (V2LY-0125-LY661)

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Target: CXCL13
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2503
Application*: N, WB
Functional Assay
Datasheet SDS

Rabbit Anti-CXCL13 Recombinant Antibody (C2963) (V2LY-0125-LY660)

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Target: CXCL13
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: C2963
Application*: IF, WB, P
Datasheet SDS

Mouse Anti-CXCL13 Recombinant Antibody (C3320) (V2LY-0125-LY658)

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Target: CXCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog
Clone: C3320
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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