CYP2A6

CYP2A6 (Cytochrome P450 Family 2 Subfamily A Member 6) is a Protein Coding gene. Diseases associated with CYP2A6 include Tobacco Addiction and Coumarin Resistance. Among its related pathways are superpathway of steroid hormone biosynthesis and superpathway of tryptophan utilization. Gene Ontology (GO) annotations related to this gene include enzyme binding and heme binding. An important paralog of this gene is CYP2A7.
Full Name
Cytochrome P450 Family 2 Subfamily A Member 6
Function
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.
Biological Process
Coumarin catabolic process Source: BHF-UCL
Coumarin metabolic process Source: BHF-UCL
Drug metabolic process Source: BHF-UCL
Epoxygenase P450 pathway Source: GO_Central
Exogenous drug catabolic process Source: BHF-UCL
Organic acid metabolic process Source: GO_Central
Steroid metabolic process Source: BHF-UCL
Xenobiotic metabolic process Source: GO_Central
Cellular Location
Endoplasmic reticulum membrane; Microsome membrane
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Anti-CYP2A6 antibodies

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Mouse Anti-CYP2A6 Recombinant Antibody (CBXC-2949) (V2LY-0125-LY948)

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Target: CYP2A6
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBXC-2949
Application*: WB, IH
Datasheet SDS

Mouse Anti-CYP2A6 Recombinant Antibody (F16 P2 D8) (V2LY-0125-LY947)

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Target: CYP2A6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: F16 P2 D8
Application*: WB, IP, IF, P
Datasheet SDS

Mouse Anti-CYP2A6 Recombinant Antibody (3B11) (V2LY-0125-LY946)

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Target: CYP2A6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3B11
Application*: E, WB
Datasheet SDS

Mouse Anti-CYP2A6 Recombinant Antibody (1D2) (V2LY-0125-LY945)

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Target: CYP2A6
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat, Monkey
Clone: 1D2
Application*: WB, F, IH
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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