DEPTOR

DEPTOR (DEP Domain Containing MTOR Interacting Protein) is a Protein Coding gene. Among its related pathways are Sirolimus Pathway, Pharmacokinetics/Pharmacodynamics and Development HGF signaling pathway.
Full Name
DEP Domain Containing MTOR Interacting Protein
Function
Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.
Biological Process
Intracellular signal transduction Source: InterPro
Negative regulation of cell size Source: UniProtKB
Negative regulation of protein kinase activity Source: UniProtKB
Negative regulation of TOR signaling Source: UniProtKB
Regulation of extrinsic apoptotic signaling pathway Source: UniProtKB
PTM
Phosphorylated. Phosphorylation weakens interaction with MTOR within mTORC1 and mTORC2.
Ubiquitinated; ubiquitination leads to proteasomal degradation.
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Anti-DEPTOR antibodies

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Mouse Anti-DEPTOR Recombinant Antibody (A2189) (V2LY-0425-LY200)

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Target: DEPTOR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: A2189
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-DEPTOR Recombinant Antibody (D0709) (V2LY-0425-LY199)

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Target: DEPTOR
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: D0709
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-DEPTOR Recombinant Antibody (D0708) (V2LY-0425-LY198)

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Target: DEPTOR
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: D0708
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-DEPTOR Recombinant Antibody (5B3) (CBMAB-A2189-LY)

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Target: DEPTOR
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5B3
Application*: SE, E
Datasheet SDS

Rabbit Anti-DEPTOR Recombinant Antibody (D9F5) (CBMAB-D0709-YC)

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Target: DEPTOR
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Monkey
Clone: D9F5
Application*: WB, IP, P
Datasheet SDS

Mouse Anti-DEPTOR Recombinant Antibody (D-2) (CBMAB-D0708-YC)

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Target: DEPTOR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: D-2
Application*: WB, IP, IF, E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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