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EAF2

EAF2 has properties characteristic for an RNA polymerase II elongation factor regulating the expression of the eye‐specific transcription factor Rx.

Full Name

ELL associated factor 2

Research Area

Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity).

Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.

Biological Process

Apoptotic process Source: UniProtKB-KW
Negative regulation of cell growth Source: Ensembl
Negative regulation of epithelial cell proliferation involved in prostate gland development Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription elongation from RNA polymerase II promoter Source: ARUK-UCL

Cellular Location

Nucleus speckle

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Anti-EAF2 antibodies

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Rabbit Anti-EAF2 Recombinant Antibody (E1R8C) (CBMAB-E0695-FY)

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Target: EAF2

Host: Rabbit

Specificity: Human

Clone: E1R8C

Application*: WB, IP, CI

Human EAF2 ELISA Kit (V2LY-0626-LY3618)

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Target: EAF2

Sensitivity: 0.00028 ng/mL

Detection Range: 0.0005-0.2 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Rabbit Anti-EAF2 Recombinant Antibody (E0695) (V2LY-0425-LY1264)

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Target: EAF2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: E0695

Application*: WB, IP

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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