Sign in or Register
  • Home
  • EAF2
  • Rabbit Anti-EAF2 Recombinant Antibody (E0695)

Rabbit Anti-EAF2 Recombinant Antibody (E0695) (V2LY-0425-LY1264)

See all EAF2 antibodies
Go to compare Compare Online Inquiry
Published Data
Rabbit Anti-EAF2 Recombinant Antibody (E0695) (V2LY-0425-LY1264-1) in WB
Rabbit Anti-EAF2 Recombinant Antibody (E0695) (V2LY-0425-LY1264-1) in WB
Relative expression of indicated genes in subcutaneous tumor tissues were quantified using western blot. ...View More
Mao, X., Ji, T., Liu, A., & Weng, Y. (2021). ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis. Cell death & disease, 12(11), 957.
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
E0695
Application
WB, IP
Immunogen
Synthetic peptide corresponding to residues near the C-terminus of human EAF2 protein.
Host Species
Rabbit
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:1,000
IP 1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
BSA & Glycerol & HEPES
Preservative
Sodium Azide
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
ELL associated factor 2
Entrez Gene ID
55840
UniProt ID
Q96CJ1
Research Area
Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity).

Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.
Biological Process
Apoptotic process Source: UniProtKB-KW
Negative regulation of cell growth Source: Ensembl
Negative regulation of epithelial cell proliferation involved in prostate gland development Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription elongation from RNA polymerase II promoter Source: ARUK-UCL
Cellular Location
Nucleus speckle

Pascal, L. E., Rigatti, L. H., Ai, J., Zhang, A., Zhou, J., Nelson, J. B., & Wang, Z. (2020). EAF2 loss induces prostatic intraepithelial neoplasia from luminal epithelial cells in mice. American journal of clinical and experimental urology, 8(1), 18.

Wn, K., Guo, F., Yc, F., Lv, J., Jh, F., Wang, Y., ... & Xm, M. (2020). Expression and gene regulation network of EAF2 in cervical cancer based on data mining.

Liu, R., Chen, C., Li, Y., Huang, Q., & Xue, Y. (2020). ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation. Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 1863(5), 194508.

Jo, Y. S., Kim, S. S., Kim, M. S., Yoo, N. J., & Lee, S. H. (2019). Candidate tumor suppressor gene EAF2 is mutated in colorectal and gastric cancers. Pathology & Oncology Research, 25(2), 823-824.

Feng, K., & Guo, H. K. (2018). Eaf2 protects human lens epithelial cells against oxidative stress‑induced apoptosis by Wnt signaling. Molecular medicine reports, 17(2), 2795-2802.

Yang, T., Jing, Y., Dong, J., Yu, X., Zhong, M., Pascal, L. E., ... & Wang, Z. (2018). Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells. The Prostate, 78(15), 1201-1212.

Zhong, M., Pascal, L. E., Cheng, E., Masoodi, K. Z., Chen, W., Green, A., ... & Wang, Z. (2018). Concurrent EAF2 and ELL2 loss phenocopies individual EAF2 or ELL2 loss in prostate cancer cells and murine prostate. American journal of clinical and experimental urology, 6(6), 234.

Zhong, M., Pascal, L., Song, Q., Chen, W., & Wang, Z. (2018, November). ELL2 and EAF2 co-regulation of AKT in prostate cancer cells. In Endocrine Abstracts (Vol. 59). Bioscientifica.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-EAF2 Recombinant Antibody (E0695)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-EAF2 Recombinant Antibody (E1R8C) (CAT#: CBMAB-E0695-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry