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EDDM3A

Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.

Full Name

Epididymal Protein 3A

Research Area

Possible function in sperm maturation.

Biological Process

Sperm displacement Source: ProtInc

Cellular Location

Secreted

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Anti-EDDM3A antibodies

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Mouse Anti-EDDM3A Recombinant Antibody (CBFYE-0434) (V2LY-0425-LY1393)

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Target: EDDM3A

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYE-0434

Application*: E, WB

Mouse Anti-EDDM3A (AA 1-147 ) Recombinant Antibody (CBFYE-0434) (CBMAB-E0754-FY)

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Target: EDDM3A

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYE-0434

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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