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ELOA

ELOA is the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. ELOA activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A plays a role as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Full Name

Elongin A

Biological Process

Regulation of transcription by RNA polymerase II Source: ProtInc
Transcription elongation from RNA polymerase II promoter Source: InterPro

Cellular Location

Nucleus

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Anti-ELOA antibodies

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Mouse Anti-ELOA Recombinant Antibody (1F3) (CBMAB-A8942-LY)

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Target: ELOA

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F3

Application*: WB, E, IF

Mouse Anti-ELOA Recombinant Antibody (CBYJT-1213) (CBMAB-T0227-YJ)

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Target: ELOA

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-1213

Application*: WB, IP, IF, E

Mouse Anti-ELOA Recombinant Antibody (CBYJT-1212) (CBMAB-T0226-YJ)

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Target: ELOA

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-1212

Application*: WB, IP, IF, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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