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ERAS

This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
Full Name
ES Cell Expressed Ras
Research Area
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity).
Biological Process
Ras protein signal transduction Source: GO_Central
Cellular Location
Cell membrane

Anti-ERAS antibodies

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Target: ERAS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1088
Application*: WB
Target: ERAS
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-1089
Application*: IF, WB
Target: ERAS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: D5G5J
Application*: WB
Target: ERAS
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP710
Application*: IF, IHC
Target: ERAS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1122
Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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