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FAM19A4

FAM19A4 is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to play a role as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells.

Full Name

Family With Sequence Similarity 19 Member A4, C-C Motif Chemokine Like

Research Area

Modulates injury-induced and chemical pain hypersensitivity (By similarity).

Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release (PubMed:25109685).

Biological Process

Macrophage chemotaxis Source: UniProtKB
Phagocytosis Source: UniProtKB
Regulation of membrane potential Source: Ensembl
Regulation of sensory perception of pain Source: Ensembl
Regulation of signaling receptor activity Source: UniProtKB
Superoxide anion generation Source: UniProtKB

Cellular Location

Secreted

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Anti-FAM19A4 antibodies

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Human Recombinant FAM19A4 protein, hFc Tag (V2LY-0526-LY4002)

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Target: FAM19A4

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 36-140

Tag: hFc Tag

Mouse Anti-FAM19A4 Recombinant Antibody (CBYJT-1277) (CBMAB-T0292-YJ)

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Target: FAM19A4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1277

Application*: WB, F

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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