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FCER1A

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
Full Name
Fc Fragment Of IgE Receptor Ia
Research Area
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Regulation of immune response Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 26-205
Helical: 206-224
Cytoplasmic: 225-257

Anti-FCER1A antibodies

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Target: FCER1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2C12-3B6
Application*: WB, E
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1648
Application*: E, F, WB
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-1427
Application*: E, F, IF, IP, WB
Target: FCER1A
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXF-3889
Application*: F, IH, IP, C
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-3512
Application*: WB, F, E, IF, IP
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: AER-37
Application*: F, WB, IF, FN
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2580
Application*: F
Target: FCER1A
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: MAR-1
Application*: F, FN, C, IP
Target: FCER1A
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1291
Application*: F
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0438
Application*: E, F, IF, IP, WB
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Rat
Clone: CBXF-0441
Application*: F, IP
Target: FCER1A
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXF-3724
Application*: FN, F
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CRA1
Application*: WB, F, IH, IC
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CRA2 AER24
Application*: F, IH, WB
Target: FCER1A
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXF-3458
Application*: F, FN, IH, IP
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 9E1
Application*: E, WB, F, IP, IF
Target: FCER1A
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXF-2393
Application*: F
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2917
Application*: E, WB
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBXF-1301
Application*: IP, F, IF
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0437
Application*: WB
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0016
Application*: E, WB, P, IF, IP
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-0017
Application*: P
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-3390
Application*: F, IC, IH, WB
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0439
Application*: E, IP
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0440
Application*: F
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0015
Application*: E, F, IF, P, IP, WB
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-0018
Application*: F, P
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-1733
Application*: WB, IP, F, E
Target: FCER1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2916
Application*: E, IP
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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