GJA4

This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

gap junction protein alpha 4

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Blood vessel development Source: Ensembl
Calcium ion transport Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Endothelium development Source: Ensembl
Response to pain Source: Ensembl

Cell membrane; Gap junction

Cytoplasmic: 1-20
Helical: 21-40
Extracellular: 41-76
Helical: 77-99
Cytoplasmic: 100-148
Helical: 149-165
Extracellular: 166-207
Helical: 208-230
Cytoplasmic: 231-333