GJA4

This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Full Name

gap junction protein alpha 4

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Biological Process

Blood vessel development Source: Ensembl
Calcium ion transport Source: Ensembl
Cell-cell junction assembly Source: ProtInc
Cell-cell signaling Source: GO_Central
Endothelium development Source: Ensembl
Response to pain Source: Ensembl

Cellular Location

Cell membrane; Gap junction

Topology

Cytoplasmic: 1-20
Helical: 21-40
Extracellular: 41-76
Helical: 77-99
Cytoplasmic: 100-148
Helical: 149-165
Extracellular: 166-207
Helical: 208-230
Cytoplasmic: 231-333

Anti-GJA4 antibodies

Mouse Anti-GJA4 Recombinant Antibody (CBLG1-1194) (CBMAB-G3552-LY)

Datasheet

SDS

Target: GJA4

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBLG1-1194

Application*: WB

Rabbit Anti-GJA4 Recombinant Antibody (EG1319) (CBMAB-EN1595-LY)

Datasheet

SDS

Target: GJA4

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1319

Application*: WB: 1:500~1:1000 ELISA: 1:40000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)