HCN3

This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 3

Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.

Cellular response to cAMP Source: ComplexPortal
Cellular response to dopamine Source: Ensembl
Potassium ion transmembrane transport Source: UniProtKB
Regulation of ion transmembrane transport Source: UniProtKB-KW
Regulation of membrane depolarization Source: ComplexPortal
Regulation of membrane potential Source: UniProtKB
Response to cisplatin Source: Ensembl
Sodium ion transmembrane transport Source: UniProtKB

Cell membrane

Cytoplasmic: 1-97
Helical: 98-118
Extracellular: 119-124
Helical: 125-145
Cytoplasmic: 146-171
Helical: 172-192
Extracellular: 193-201
Helical: 202-222
Cytoplasmic: 223-253
Helical: 254-274
Extracellular: 275-297
Pore-forming: 298-319
Extracellular: 320-329
Helical: 330-350
Cytoplasmic: 351-774