HCN3

This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Full Name
Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 3
Function
Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.
Biological Process
Cellular response to cAMP Source: ComplexPortal
Cellular response to dopamine Source: Ensembl
Potassium ion transmembrane transport Source: UniProtKB
Regulation of ion transmembrane transport Source: UniProtKB-KW
Regulation of membrane depolarization Source: ComplexPortal
Regulation of membrane potential Source: UniProtKB
Response to cisplatin Source: Ensembl
Sodium ion transmembrane transport Source: UniProtKB
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-97
Helical: 98-118
Extracellular: 119-124
Helical: 125-145
Cytoplasmic: 146-171
Helical: 172-192
Extracellular: 193-201
Helical: 202-222
Cytoplasmic: 223-253
Helical: 254-274
Extracellular: 275-297
Pore-forming: 298-319
Extracellular: 320-329
Helical: 330-350
Cytoplasmic: 351-774
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Anti-HCN3 antibodies

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Mouse Anti-HCN3 Recombinant Antibody (S141-28) (CBMAB-AP2677LY)

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Target: HCN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: S141-28
Application*: ICC/IF, AM, IHC, WB
Datasheet SDS

Mouse Anti-HCN3 (C-terminus) Recombinant Antibody (CBFYH-3541) (CBMAB-H4093-FY)

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Target: HCN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBFYH-3541
Application*: IC, IF, IH, IP, WB
Datasheet SDS

Mouse Anti-HCN3 (AA 660-779 ) Recombinant Antibody (CBFYH-0785) (CBMAB-H0275-FY)

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Target: HCN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYH-0785
Application*: WB, IH, IF
Datasheet SDS

Mouse Anti-HCN3 (AA 660-779 ) Recombinant Antibody (CBFYH-0784) (CBMAB-H0274-FY)

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Target: HCN3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYH-0784
Application*: WB, P, IF
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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