HTR5A

The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
Full Name
5-Hydroxytryptamine Receptor 5A
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: Ensembl
Adenylate cyclase-inhibiting serotonin receptor signaling pathway Source: GO_Central
Chemical synaptic transmission Source: GO_Central
G protein-coupled receptor signaling pathway Source: ProtInc
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: GO_Central
Hippocampus development Source: Ensembl
Response to estradiol Source: Ensembl
Cellular Location
Cell membrane
Topology
Extracellular: 1-40
Helical: 41-63
Cytoplasmic: 64-78
Helical: 79-99
Extracellular: 100-115
Helical: 116-137
Cytoplasmic: 138-158
Helical: 159-181
Extracellular: 182-198
Helical: 199-219
Cytoplasmic: 220-282
Helical: 283-303
Extracellular: 304-320
Helical: 321-341
Cytoplasmic: 342-357
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Anti-HTR5A antibodies

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Rabbit Anti-HTR5A Recombinant Antibody (EG1593) (CBMAB-EN1906-LY)

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Target: HTR5A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1593
Application*: WB: 1:500~1:1000 ELISA: 1:20000
Datasheet SDS

Mouse Anti-HTR5A Recombinant Antibody (3D1) (CBMAB-A4156-LY)

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Target: HTR5A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Rat
Clone: 3D1
Application*: WB, E
Datasheet SDS

Mouse Anti-HTR5A Recombinant Antibody (10D3) (CBMAB-A4155-LY)

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Target: HTR5A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 10D3
Application*: WB, E
Datasheet SDS

Mouse Anti-HTR5A (AA 223-282) Recombinant Antibody (CBFYH-2505) (CBMAB-H3519-FY)

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Target: HTR5A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-2505
Application*: E, WB
Datasheet SDS

Mouse Anti-HTR5A (AA 223-283) Recombinant Antibody (CBFYH-2504) (CBMAB-H3518-FY)

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Target: HTR5A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-2504
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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