IFT88

This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2017]
Full Name
Intraflagellar Transport 88
Function
Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
Biological Process
Cilium assembly Source: UniProtKB
Inner ear receptor cell stereocilium organization Source: GO_Central
Intraciliary transport Source: GO_Central
Kidney development Source: GO_Central
Non-motile cilium assembly Source: GO_Central
Regulation of autophagosome assembly Source: UniProtKB
Regulation of cilium assembly Source: UniProtKB
Cellular Location
Centriole; Cilium basal body; Centrosome; Cytoplasm; Cilium; Flagellum. Colocalizes with ENTR1 and gamma-tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome.
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Anti-IFT88 antibodies

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Mouse Anti-IFT88 Recombinant Antibody (A424) (CBMAB-AP10814LY)

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Target: IFT88
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: A424
Application*: ELISA, IF, IHC, WB
Datasheet SDS

Mouse Anti-IFT88 Recombinant Antibody (CF215) (CBMAB-FT258LY)

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Target: IFT88
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CF215
Application*: ELISA, WB, IHC, IP
Datasheet SDS

Rabbit Anti-IFT88 Recombinant Antibody (CBYJT-1387) (CBMAB-T0409-YJ)

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Target: IFT88
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-1387
Application*: WB, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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