IL17RB

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Full Name
Interleukin 17 Receptor B
Function
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Biological Process
Defense response Source: ProtInc
Regulation of cell growth Source: UniProtKB
Cellular Location
Isoform 1: Cell membrane
Isoform 2: Secreted
Topology
Extracellular: 18-292
Helical: 293-313
Cytoplasmic: 314-502
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Anti-IL17RB antibodies

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Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I1560
Application*: F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I1320
Application*: E, WB
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-I1094
Application*: F, WB
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 9J28
Application*: WB
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I0822
Application*: F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 97C691
Application*: WB, IH
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0816
Application*: WB, F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0815
Application*: F, MC
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0814
Application*: IH, P, IC
Target: IL17RB
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 752101
Application*: F, MC
Target: IL17RB
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBYY-I0703
Application*: F
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I0365
Application*: F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0339
Application*: WB
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0152
Application*: WB, ED, MC, F
Target: IL17RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0151
Application*: WB, E
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 152316
Application*: WB
Target: IL17RB
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 152309
Application*: WB, E
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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