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IL3

The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]

Full Name

Interleukin 3

Function

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.

Biological Process

Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Embryonic hemopoiesisManual Assertion Based On ExperimentIDA:DFLAT
Immune responseIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of peptidyl-tyrosine phosphorylationISS:UniProtKB
Positive regulation of tyrosine phosphorylation of STAT proteinManual Assertion Based On ExperimentIDA:BHF-UCL

Cellular Location

Secreted

Anti-IL3 antibodies

Mouse Anti-IL3 Recombinant Antibody (A550) (CBMAB-AP3754LY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: A550

Application*: Sandwich ELISA, WB, Neutralization

Mouse Anti-IL3 Recombinant Antibody (CBYY-I2107) (CBMAB-I3277-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I2107

Application*: WB

Mouse Anti-IL3 Recombinant Antibody (CBYY-I2023) (CBMAB-I3193-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I2023

Application*: WB, IH, IF

Rat Anti-IL3 Recombinant Antibody (CBYY-I1703) (CBMAB-I2873-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBYY-I1703

Application*: ED, N, WB

Rat Anti-IL3 Recombinant Antibody (CBYY-I1392) (CBMAB-I2562-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBYY-I1392

Application*: N, WB

Mouse Anti-IL3 Recombinant Antibody (CBYY-I1120) (CBMAB-I2288-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYY-I1120

Application*: E

Mouse Anti-IL3 Recombinant Antibody (CBYY-I1119) (CBMAB-I2287-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-I1119

Application*: E

Mouse Anti-IL3 Recombinant Antibody (CBYY-I0825) (CBMAB-I1855-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBYY-I0825

Application*: N

Mouse Anti-IL3 Recombinant Antibody (CBYY-I0686) (CBMAB-I1515-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Dog

Clone: CBYY-I0686

Application*: IC

Rat Anti-IL3 Recombinant Antibody (CBYY-I0666) (CBMAB-I1479-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBYY-I0666

Application*: E, WB

Rat Anti-IL3 Recombinant Antibody (CBYY-I0649) (CBMAB-I1462-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-I0649

Application*: E, F, IF

Rat Anti-IL3 Recombinant Antibody (CBYY-I0648) (CBMAB-I1461-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-I0648

Application*: E, N, WB

Mouse Anti-IL3 Recombinant Antibody (5G7H9) (CBMAB-I1451-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5G7H9

Application*: WB

Mouse Anti-IL3 Recombinant Antibody (5D7) (CBMAB-I1437-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 5D7

Application*: E

Human Anti-IL3 Recombinant Antibody (4E6, 2F2, 3C11) (CBMAB-I1331-YY)

SDS

Target: IL3

Host: Human

Antibody Isotype: IgG1, IgG2a

Specificity: Human

Clone: 4E6, 2F2, 3C11

Application*: E

Rat Anti-IL3 Recombinant Antibody (BVD8-3G11) (CBMAB-I1195-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG1

Specificity: Human

Clone: BVD8-3G11

Application*: EC, WB, IP, N, BL

Rat Anti-IL3 Recombinant Antibody (BVD3-1F9) (CBMAB-I1192-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG1

Specificity: Human

Clone: BVD3-1F9

Application*: ED, F, C, WB, IP, IS

Rat Anti-IL3 Recombinant Antibody (CBYY-I0348) (CBMAB-I0896-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse

Clone: CBYY-I0348

Application*: F, E, IH, IF, IP, C, BL, N, IC

Rat Anti-IL3 Recombinant Antibody (MP2-43D11) (CBMAB-I0895-YY)

SDS

Target: IL3

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: MP2-43D11

Application*: E, WB, C, IC, WB, ED, IC

Mouse Anti-IL3 Recombinant Antibody (2F2) (CBMAB-I0546-YY)

SDS

Target: IL3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2F2

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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