IL3

The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
Full Name
Interleukin 3
Function
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
Biological Process
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Embryonic hemopoiesisManual Assertion Based On ExperimentIDA:DFLAT
Immune responseIEA:InterPro
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of peptidyl-tyrosine phosphorylationISS:UniProtKB
Positive regulation of tyrosine phosphorylation of STAT proteinManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Secreted
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Anti-IL3 antibodies

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Mouse Anti-IL3 Recombinant Antibody (A550) (CBMAB-AP3754LY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A550
Application*: Sandwich ELISA, WB, Neutralization
Functional Assay
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (CBYY-I2107) (CBMAB-I3277-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I2107
Application*: WB
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (CBYY-I2023) (CBMAB-I3193-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I2023
Application*: WB, IH, IF
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (CBYY-I1703) (CBMAB-I2873-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-I1703
Application*: ED, N, WB
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (CBYY-I1392) (CBMAB-I2562-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I1392
Application*: N, WB
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (CBYY-I1120) (CBMAB-I2288-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I1120
Application*: E
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (CBYY-I1119) (CBMAB-I2287-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I1119
Application*: E
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (CBYY-I0825) (CBMAB-I1855-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-I0825
Application*: N
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (CBYY-I0686) (CBMAB-I1515-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog
Clone: CBYY-I0686
Application*: IC
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (CBYY-I0666) (CBMAB-I1479-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: CBYY-I0666
Application*: E, WB
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (CBYY-I0649) (CBMAB-I1462-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0649
Application*: E, F, IF
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (CBYY-I0648) (CBMAB-I1461-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0648
Application*: E, N, WB
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (5G7H9) (CBMAB-I1451-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5G7H9
Application*: WB
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (5D7) (CBMAB-I1437-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D7
Application*: E
Datasheet SDS

Human Anti-IL3 Recombinant Antibody (4E6, 2F2, 3C11) (CBMAB-I1331-YY)

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Target: IL3
Host: Human
Antibody Isotype: IgG1, IgG2a
Specificity: Human
Clone: 4E6, 2F2, 3C11
Application*: E
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (BVD8-3G11) (CBMAB-I1195-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: BVD8-3G11
Application*: EC, WB, IP, N, BL
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (BVD3-1F9) (CBMAB-I1192-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: BVD3-1F9
Application*: ED, F, C, WB, IP, IS
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (CBYY-I0348) (CBMAB-I0896-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBYY-I0348
Application*: F, E, IH, IF, IP, C, BL, N, IC
Datasheet SDS

Rat Anti-IL3 Recombinant Antibody (MP2-43D11) (CBMAB-I0895-YY)

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Target: IL3
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: MP2-43D11
Application*: E, WB, C, IC, WB, ED, IC
Datasheet SDS

Mouse Anti-IL3 Recombinant Antibody (2F2) (CBMAB-I0546-YY)

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Target: IL3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2F2
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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